[Pharmacovigilance update].

Author: BuclinThierry, ChtiouiHaithem, DaoKim, DieziLéonore, LivioFrançoise, Prod'homSylvain, RothuizenLaura E, WinterfeldUrsula

Paper Details 
Original Abstract of the Article :
The main pharmacovigilance updates in 2015are reviewed. Sofosbuvir amiodarone interaction: risk of severe bradycardia. Dasabuvir clopidogrel interaction: increased dasabuvir concentrations and potential risk of QTprolongation. SGLT2 inhibitors: risks of diabetic acidocetosis and bone fracture. Dabig...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/26946710

データ提供:米国国立医学図書館(NLM)

Pharmacovigilance Update: A Guide to Navigating Drug Safety

The field of pharmacovigilance is constantly evolving as new drugs are developed and their safety profiles are further investigated. This review article provides a comprehensive overview of key pharmacovigilance updates that emerged in 2015, highlighting important drug interactions, potential risks, and evolving recommendations for safe and effective medication use.

The article covers a wide range of topics, including the potential for severe bradycardia when combining sofosbuvir with amiodarone, the risk of QT prolongation associated with the interaction between dasabuvir and clopidogrel, and the emerging concerns regarding diabetic ketoacidosis and bone fractures in patients using SGLT2 inhibitors. It also discusses the potential benefits of therapeutic drug monitoring for dabigatran, the comparable vascular risks of higher doses of ibuprofen to coxibs, and the potential for abuse and addiction associated with pregabalin and gabapentin.

Staying Informed: A Crucial Part of Drug Safety

This review serves as a valuable resource for healthcare professionals and patients alike, highlighting the importance of staying informed about drug safety updates and potential risks associated with medications. It underscores the need for continued vigilance and collaboration between healthcare providers and patients to ensure safe and effective medication use.

Navigating the Sands of Medication Safety

The world of medications is complex, and staying informed about the latest safety recommendations is essential. This review serves as a helpful guide for navigating the potential risks and benefits associated with various medications. Remember, open communication with your healthcare provider is key for ensuring safe and effective medication use.

Dr. Camel's Conclusion

Just as a camel carefully navigates the unpredictable desert landscape, it's vital to approach medication use with caution and awareness. This pharmacovigilance update provides valuable insights into the evolving safety profiles of various medications, highlighting the importance of staying informed and collaborating with healthcare professionals to ensure optimal patient safety.

Date :
  1. Date Completed 2016-03-21
  2. Date Revised 2016-03-07
Further Info :

Pubmed ID

26946710

DOI: Digital Object Identifier

26946710

Related Literature

SNS
PICO Info
in preparation
Languages

French

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