Electroacupuncture Enhances the Antiallodynic and Antihyperalgesic Effects of Milnacipran in Neuropathic Rats.

Author: JiByeong Uk, KimNam-Kwen, KimSeung Tae, KimYiquot, KooSungtae, LeeJi Eun, LiChengjin

Paper Details 
Original Abstract of the Article :
Milnacipran, a selective serotonin/norepinephrine-reuptake inhibitor, has been shown to elicit a beneficial effect in various models of neuropathic pain. Previously, we reported that repetitive electroacupuncture (EA) significantly ameliorates neuropathic pain induced by L5 spinal nerve ligation (SN...See full text at original site
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引用元:
https://doi.org/10.1213/ANE.0000000000001212

データ提供:米国国立医学図書館(NLM)

Electroacupuncture and Milnacipran: Synergistic Relief for Neuropathic Pain

Neuropathic pain is a debilitating condition characterized by chronic pain that arises from damage to the nervous system. This pain can be like a scorching desert wind, relentless and difficult to alleviate. Milnacipran, a serotonin/norepinephrine reuptake inhibitor, has shown some effectiveness in managing neuropathic pain, but its effects can be limited. This study explores the potential of combining electroacupuncture (EA) with milnacipran to enhance pain relief.

The research focused on rats with neuropathic pain induced by L5 spinal nerve ligation. The study found that a single session of EA significantly reduced pain, suggesting that EA alone can provide relief. Moreover, combining a sub-effective dose of milnacipran with EA produced a synergistic effect, significantly improving pain relief compared to either treatment alone. This finding suggests that EA and milnacipran, when used together, might offer a more effective approach to managing neuropathic pain.

A New Oasis for Pain Relief: Combining Acupuncture and Medication

This study suggests that combining EA with milnacipran could offer a more effective approach to managing neuropathic pain. This combination might help patients find relief from the relentless pain, improving their quality of life and allowing them to more easily navigate the challenging desert of chronic pain.

A Multifaceted Approach: Harnessing the Power of Acupuncture and Medications

Neuropathic pain can be a challenging and persistent desert storm. This study suggests that a multifaceted approach, combining the ancient wisdom of acupuncture with modern medications, might offer a more effective and sustainable path to pain relief.

Dr. Camel's Conclusion

This research, like a cool breeze in a scorching desert, offers a glimmer of hope for those suffering from neuropathic pain. Combining electroacupuncture with milnacipran can provide enhanced pain relief, offering a potential oasis for those navigating this challenging journey. Further research is needed to validate these findings, but this study provides a promising direction for alleviating chronic pain and improving quality of life for those affected.

Date :
  1. Date Completed 2016-09-07
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26962713

DOI: Digital Object Identifier

10.1213/ANE.0000000000001212

Related Literature

SNS
PICO Info
in preparation
Languages

English

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