Toxicity and early outcomes of regorafenib in multiply pre-treated metastatic colorectal adenocarcinoma-experience from a tertiary cancer centre in India.

Author: BanavaliShripad, GuptaSudeep, OstwalVikas, ShettyNitin, SirohiBhawna, ToshniwalAnup, ZanwarSaurabh

Paper Details 
Original Abstract of the Article :
BACKGROUND: Regorafenib is a multikinase inhibitor (MKI) approved for use in multiply pre-treated metastatic colorectal cancers (mCRC). To the best of our knowledge, this is the first report of regorafenib from India. MATERIALS AND METHODS: Records of 23 cases treated with regorafenib at our centre...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779767/

データ提供:米国国立医学図書館(NLM)

Regorafenib: A Powerful Tool in the Fight Against Colorectal Cancer

Metastatic colorectal cancer, like a persistent desert sandstorm, poses a significant threat to human health. Regorafenib, a multikinase inhibitor, has emerged as a powerful weapon in the fight against this aggressive disease, but its effectiveness comes with potential side effects.

This study, like a meticulous physician, examines the toxicity and outcomes of regorafenib treatment for patients with metastatic colorectal cancer in India. It provides valuable data on the efficacy and side effect profile of this drug in a real-world setting, offering crucial insights for clinical decision-making.

The study found that while regorafenib can be an effective treatment, it is associated with significant side effects, such as hand-foot syndrome and fatigue. The authors emphasize the importance of careful monitoring and management of these side effects to optimize treatment outcomes.

Navigating the Side Effects of Regorafenib

This study highlights the importance of careful patient monitoring during regorafenib treatment. Managing potential side effects effectively, like a skilled guide navigating a treacherous desert path, is crucial for maximizing the benefits of this powerful therapy.

A Journey Towards a Healthier Future

This study underscores the importance of comprehensive care for patients with metastatic colorectal cancer. By carefully managing the side effects of regorafenib, we can optimize its efficacy and improve the quality of life for those battling this challenging disease, offering a glimmer of hope in the face of adversity.

Dr.Camel's Conclusion

This study provides a valuable assessment of regorafenib's efficacy and safety profile in treating metastatic colorectal cancer. It highlights the need for ongoing research to develop strategies for managing potential side effects, ensuring that patients can benefit from this promising therapeutic option while maintaining a good quality of life.

Date :
  1. Date Completed 2016-03-23
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

27004221

DOI: Digital Object Identifier

PMC4779767

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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