Worsening of myasthenia gravis after administration of injectable long-acting risperidone for treatment of schizophrenia; first case report and a call for caution.

Author: Al-HashelJasem Y, AliMahmoud, IbrahimMohammed, IsmailIsmail Ibrahim, JohnJohn K

Paper Details 
Original Abstract of the Article :
Myasthenia gravis is an autoimmune disease characterized by muscle weakness due to autoantibodies affecting the neuromuscular junction. Co-occurrence of myasthenia gravis and schizophrenia is very rare and raises a challenge in management of both diseases. Antipsychotic drugs exhibit anticholinergic...See full text at original site
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引用元:
https://doi.org/10.1016/j.nmd.2016.02.006

データ提供:米国国立医学図書館(NLM)

Myasthenia Gravis and Schizophrenia: A Complex Duo

Myasthenia gravis, an autoimmune disease characterized by muscle weakness, can sometimes partner up with schizophrenia, a mental health disorder. This pairing is rare, making it a true challenge for doctors. Antipsychotic drugs, like long-acting risperidone, can be helpful for schizophrenia, but they can also have side effects, like anticholinergic effects, which can worsen myasthenia gravis.

This study delves into a case of a 29-year-old woman who had both myasthenia gravis and schizophrenia. She experienced a worsening of her myasthenia symptoms after receiving long-acting risperidone injections. This was the first time such a reaction was reported, making it a 'first case report,' and a call for caution in using this medication in those with myasthenia gravis. The researchers suspect this side effect is linked to how long the drug remains active in the body.

A New Warning for Long-Acting Risperidone

This research sheds light on a potential side effect of long-acting risperidone. The researchers recommend caution in its use for individuals with myasthenia gravis. Doctors need to be aware of this potential risk and carefully monitor patients on this medication for signs of myasthenia worsening.

Navigating the Desert of Complex Conditions

Myasthenia gravis and schizophrenia are like two sandstorms in the desert of the human body. Each one presents its own challenges, and when they combine, they create a complex and difficult landscape for patients and doctors to navigate. This study serves as a reminder that medication can have unexpected effects in those with complex conditions. It underscores the importance of careful monitoring and open communication between patients and their healthcare providers.

Dr.Camel's Conclusion

This study serves as a valuable guidepost in the vast desert of medical knowledge, reminding us that even seemingly safe medications can have unexpected impacts, especially when dealing with complex conditions. The desert of medical knowledge is always changing, and we need to be vigilant in our research to ensure the best possible care for our patients.

Date :
  1. Date Completed 2017-01-03
  2. Date Revised 2017-01-04
Further Info :

Pubmed ID

27012182

DOI: Digital Object Identifier

10.1016/j.nmd.2016.02.006

SNS
PICO Info
in preparation
Languages

English

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