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The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology.
Author: BelardinelliLuiz, BraunInga, DannerBernhard C, DobrevDobromir, FischerThomas H, FreyNorbert, GummertJan, HartmannNico, HasenfussGerd, MaierLars S, MasonFleur E, PabelSteffen, RennerAndré, SchotolaHanna, SossallaSamuel, VoigtNiels
Original Abstract of the Article :
Pharmacological rhythm control of atrial fibrillation (AF) in patients with structural heart disease is limited. Ranolazine in combination with low dose dronedarone remarkably reduced AF-burden in the phase II HARMONY trial. We thus aimed to investigate the possible mechanisms underlying these resul...See full text at original site
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引用元:
https://doi.org/10.1016/j.yjmcc.2016.03.012
データ提供:米国国立医学図書館(NLM)
Investigating the Synergistic Effects of Ranolazine and Dronedarone for Atrial Fibrillation Management
The field of [cardiology] is constantly seeking new ways to manage [atrial fibrillation], a common heart rhythm disorder. This study delves into the potential benefits of combining [ranolazine] and [dronedarone] for patients with [structural heart disease]. Building upon the promising results of the [HARMONY trial], researchers aim to uncover the mechanisms underlying the effectiveness of this drug combination. By investigating the electrophysiological effects of [ranolazine] and [dronedarone], the authors seek to provide a deeper understanding of how these medications work together to control [atrial fibrillation] and improve patient outcomes.
Potential for Improved Rhythm Control in Atrial Fibrillation
The study explores the potential of combining [ranolazine] and [dronedarone] to achieve better rhythm control in patients with [atrial fibrillation]. This combination therapy might offer a valuable alternative for patients who haven't responded well to other treatment options. Further research is needed to confirm the long-term efficacy and safety of this combination therapy.
Maintaining Heart Health: Understanding Atrial Fibrillation
It's important to be aware of the potential risks associated with [atrial fibrillation], a heart rhythm disorder that can lead to complications like [stroke]. Maintaining a healthy lifestyle, including [regular exercise] and [a balanced diet], and seeking prompt medical attention for any concerning symptoms can help prevent or manage [atrial fibrillation]. Just as a camel adapts to survive in a desert environment, we must learn to understand and care for our hearts, ensuring their optimal function.
Dr.Camel's Conclusion
This research offers valuable insights into the potential of combining [ranolazine] and [dronedarone] for the management of [atrial fibrillation]. Further investigation is crucial to fully understand the benefits and risks associated with this combination therapy. This study reminds us that the quest for effective treatments for heart rhythm disorders is an ongoing journey, demanding continual exploration and innovation.
Date :
- Date Completed 2017-05-31
- Date Revised 2018-12-02
Further Info :
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