Atypical onset of bicalutamide-induced liver injury.

Author: JooJong Seok, KangSun Hyoung, KimJu Seok, KimKyung Hee, KimSeok Hyun, KimSeok Won, LeeByung Seok, LeeEaum Seok, LeeHeon Young, MoonHee Seok, SungJae Kyu, YunGee Young

Paper Details 
Original Abstract of the Article :
Anti-androgen therapy is the leading treatment for advanced prostate cancer and is commonly used for neoadjuvant or adjuvant treatment. Bicalutamide is a non-steroidal anti-androgen, used during the initiation of androgen deprivation therapy along with a luteinizing hormone-releasing hormone agonist...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823258/

データ提供:米国国立医学図書館(NLM)

Bicalutamide-Induced Liver Injury: A Case Study of Delayed Onset

The use of medications, while often beneficial, can sometimes come with unintended consequences. This case study investigates an instance of delayed liver injury associated with bicalutamide, a medication commonly used for prostate cancer. This rare case highlights the importance of careful monitoring of liver function throughout treatment, even in the absence of immediate side effects.

A Rare Case of Delayed Liver Injury: A Reminder of Vigilance

The case study presents a rare instance of bicalutamide-induced hepatotoxicity developing five months after treatment initiation, a delayed onset not typically seen with this medication. This observation underscores the importance of monitoring liver function over the long term during bicalutamide treatment, even in the absence of immediate side effects. The researchers emphasize the need for vigilant monitoring and prompt intervention in the event of liver injury, promoting patient safety and optimal outcomes.

Staying Informed: Managing Medications Safely

If you are taking bicalutamide or any other medication, it's important to stay informed about potential side effects and maintain open communication with your healthcare provider. Regular monitoring of liver function and prompt reporting of any unusual symptoms can help ensure early detection and management of potential complications. Understanding the potential risks and benefits of medications, along with proactive monitoring, is crucial for maximizing therapeutic benefits and minimizing adverse effects.

Dr.Camel's Conclusion

This case study, much like a camel encountering an unexpected mirage in the desert, serves as a reminder of the importance of vigilance in managing medications. The delayed onset of liver injury highlights the need for ongoing monitoring of liver function throughout treatment, even for medications that are generally well-tolerated. This case underscores the importance of patient education, open communication with healthcare providers, and proactive monitoring for optimal patient safety and therapeutic outcomes.

Date :
  1. Date Completed 2017-01-17
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

27099451

DOI: Digital Object Identifier

PMC4823258

Related Literature

SNS
PICO Info
in preparation
Languages

English

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