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Verapamil Inhibits the Pelvic Pressure Increase Corresponding to Flow Perfusion in the Porcine Percutaneous Renal Puncture Model.
Author: LuJun, ShaMinglei, ShaoYi, SunFeng, WeiHaibin, XiaShujie
Original Abstract of the Article :
PURPOSE: To estimate the effects of verapamil on pelvic pressure and investigate the possible systemic side effects in the porcine model during the procedure of increasing perfusion rates. MATERIALS AND METHODS: In the experimental group, the pelvic pressure was recorded with increasing perfusion r...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1159/000443967
データ提供:米国国立医学図書館(NLM)
A New Approach to Renal Puncture: The Role of Verapamil
Renal puncture, a common procedure used to diagnose and treat kidney problems, can sometimes be a bit tricky. Imagine a camel trying to navigate a narrow, rocky path - sometimes, the pressure can be intense. This study, like a skilled camel herder, focuses on reducing the pressure build-up during renal puncture. Researchers explored the potential benefits of verapamil, a calcium channel blocker, in minimizing this pressure. They conducted an experiment using a porcine model, mimicking the conditions of a real-life renal puncture procedure.
A Pressure-Free Puncture
The researchers carefully adjusted the flow rate of fluid into the renal pelvis, simulating the pressure changes that occur during the procedure. They observed that increasing concentrations of verapamil effectively reduced the pelvic pressure, creating a more comfortable environment for the procedure. Interestingly, even with the increased flow rates and verapamil concentrations, the animals' blood pressure and heart rate remained stable, indicating that verapamil is safe and doesn't cause any harmful side effects.
Safe and Effective for Kidney Health
Think of verapamil as a soothing oasis in the desert of kidney health. This study suggests that verapamil could be a valuable tool for minimizing discomfort and improving the overall experience of renal puncture. It's a testament to the power of scientific exploration, uncovering new ways to make medical procedures safer and more effective.
Dr. Camel's Conclusion
This research demonstrates the potential of verapamil to enhance the safety and effectiveness of renal puncture procedures. By reducing pressure and minimizing the risk of complications, verapamil can make this procedure more comfortable and beneficial for patients.
Date :
- Date Completed 2018-04-26
- Date Revised 2018-12-02
Further Info :
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