Paper Details

  1. Home
  2. Paper Details

Clinical experience with repository corticotropin injection in patients with multiple sclerosis experiencing mood changes with intravenous methylprednisolone: a case series.

Author: MurrayStacey, WooAndrew

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This report describes six cases of relapsing-remitting multiple sclerosis (MS) patients who experienced detrimental mood changes with methylprednisolone (MP) treatment. All six patients subsequently showed improvements in MS symptoms after receiving repository corticotropin injection, suggesting that it may be a viable alternative for treating acute exacerbations of MS, particularly in patients with a history of neuropsychiatric disorders.
Paper Details　
Original Abstract of the Article :
The elevated prevalence of neuropsychiatric symptoms and disorders among patients with multiple sclerosis (MS) is well recognized, as are potential neuropsychiatric side effects of treatment with corticosteroids. Both methylprednisolone (MP) and repository corticotropin injection (HP Acthar(®) gel) ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811008/

データ提供：米国国立医学図書館（NLM）

Repository Corticotropin Injection: An Alternative for MS Patients with Mood Changes

Multiple sclerosis (MS) is a chronic neurological condition that disrupts the flow of information in the brain and spinal cord. This study explores the use of repository corticotropin injection (HP Acthar® gel) for treating MS exacerbations in patients who have experienced detrimental mood changes with intravenous methylprednisolone, a commonly used corticosteroid. It's like finding a calmer oasis in a desert storm, offering a gentler approach for individuals with MS who struggle with mood fluctuations.

Repository Corticotropin Injection: A Potentially Safer Alternative

The study suggests that repository corticotropin injection may be a viable alternative for MS patients who experience mood changes with methylprednisolone. This is like finding a different path through a desert, choosing a route that avoids a treacherous sandstorm. The study highlights the potential benefits of repository corticotropin injection in managing MS exacerbations without triggering unwanted mood fluctuations.

Addressing Neuropsychiatric Complications in MS

The study also emphasizes the importance of considering the potential for neuropsychiatric side effects when treating MS. This is like navigating a desert landscape with its hidden dangers, requiring vigilance and careful planning. The study encourages further research into the potential efficacy and safety of repository corticotropin injection in managing neuropsychiatric complications associated with MS.

Dr.Camel's Conclusion

This study is a testament to the ongoing search for safer and more effective treatments for MS, a journey like a caravan seeking a cure for this challenging disease. By exploring alternative therapies like repository corticotropin injection, we can offer a more personalized approach to managing MS and its associated challenges, creating a more comfortable journey for those living with this condition.

Date :
  1. Date Completed 2016-05-02
  2. Date Revised 2020-10-01
Further Info :

Pubmed ID

27134674

DOI: Digital Object Identifier

PMC4811008

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.