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Preclinical evaluation of (99m)Tc labeled chondroitin sulfate for monitoring of cartilage degeneration in osteoarthritis.
Author: HackerMarcus, KosikSiegfried, MenzelJohannes, PagitzMaximilian, SobalGrazyna, VelusamyKavitha
Original Abstract of the Article :
PURPOSE: In previous in-vitro and ex-vivo studies we proved the specific uptake of (99m)Tc radiolabeled chondroitin sulfate (CS) in human articular cartilage. As a logical next step for the clinical use for imaging osteoarthritis we investigated in-vivo uptake of (99m)TcCS in dogs. PROCEDURES: The ...See full text at original site
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引用元:
https://doi.org/10.1016/j.nucmedbio.2016.02.009
データ提供:米国国立医学図書館(NLM)
(99m)Tc Labeled Chondroitin Sulfate: A New Tool for Monitoring Cartilage Degeneration
This research explores the potential of [(99m)Tc labeled chondroitin sulfate (CS)] as a diagnostic tool for imaging [cartilage degeneration] in [osteoarthritis]. The authors build on previous [in-vitro] and [ex-vivo] studies, demonstrating the [specific uptake] of [(99m)TcCS] in [human articular cartilage]. The study investigates the [in-vivo] uptake of [(99m)TcCS] in [dogs] with [osteoarthritis], providing evidence for its potential as a [non-invasive] imaging technique to detect and monitor cartilage degeneration.
A New Oasis in the Desert of Osteoarthritis Diagnosis
The study demonstrates the potential of [(99m)TcCS] to detect and monitor [cartilage degeneration] in [osteoarthritis]. Imagine finding a hidden oasis in a vast desert, revealing a source of knowledge and understanding. This is the kind of breakthrough [(99m)TcCS] could offer for diagnosing and managing [osteoarthritis]. The study highlights the importance of developing [non-invasive] imaging techniques to improve the diagnosis and treatment of [osteoarthritis], a condition affecting millions worldwide.
A Promising Path to Better Osteoarthritis Management
This research paves the way for a new era of [osteoarthritis] management, offering a potentially more effective and efficient approach to diagnosis and monitoring. The study underscores the importance of [innovation] in the field of [imaging], seeking to find new ways to improve the lives of [osteoarthritis] patients. This research is a reminder that even in the face of complex medical challenges, there are always new frontiers to explore and innovative solutions to discover.
Dr.Camel's Conclusion
This study is a beacon of hope in the arid landscape of [osteoarthritis] research. The potential of [(99m)TcCS] as a diagnostic tool for [cartilage degeneration] is truly exciting, offering a potentially [non-invasive] and [effective] method for monitoring disease progression. The researchers have made significant strides in developing [imaging techniques] for [osteoarthritis], paving the way for a more targeted and effective approach to treatment.
Date :
- Date Completed 2017-11-17
- Date Revised 2017-12-06
Further Info :
Related Literature
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