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Preclinical studies of VS-505: a non-absorbable highly effective phosphate binder.

Author: ChenYung-Wu, WessaleJerry L, WongJonathan T, Wu-WongJ Ruth

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

VS-505 is a novel, non-absorbable phosphate binder derived from plants. Preclinical studies showed promising results, suggesting its potential for treating phosphate imbalance in chronic kidney disease (CKD) patients.
Paper Details　
Original Abstract of the Article :
Phosphate imbalance is often present in chronic kidney disease (CKD), and it contributes to a higher cardiovascular mortality rate. A phosphate binder is typically part of a treatment strategy for controlling phosphate imbalance. However, safety concerns and low compliance are two well-recognized di...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919576/

データ提供：米国国立医学図書館（NLM）

VS-505: A New Oasis in the Desert of Phosphate Imbalance

Phosphate imbalance is a common complication of chronic kidney disease (CKD). Imagine a desert where the delicate balance of water and minerals is disrupted, leading to a cascade of health problems. This study introduces VS-505, a non-absorbable phosphate binder that could offer relief for patients with CKD. It's like discovering a hidden oasis in the desert, capable of restoring balance and promoting health.

Restoring Balance in the Desert of CKD

VS-505 is a calcium- and aluminum-free, plant-derived polymer that effectively binds phosphate in the digestive system. This could be a game-changer for CKD patients, providing a safe and effective treatment option for managing phosphate imbalance. The researchers are conducting clinical trials to evaluate its effectiveness and safety in hemodialysis patients.

Navigating the Desert of CKD with VS-505

VS-505 holds great promise for CKD patients, offering a potential solution for managing phosphate imbalance. However, further research is needed to fully assess its long-term safety and efficacy. By continuing to explore innovative treatments like VS-505, we can work towards finding a cure for CKD and improving the lives of countless individuals.

Dr.Camel's Conclusion

This study presents a glimmer of hope in the desert of CKD, with VS-505 offering a potential solution for managing phosphate imbalance. Just as an oasis provides water and sustenance in a harsh desert, VS-505 could offer a lifeline for patients struggling with CKD. As the research continues, we are closer to finding a way to restore balance and improve the lives of those living with this challenging condition.

Date :
  1. Date Completed 2017-10-17
  2. Date Revised 2021-01-09
Further Info :

Pubmed ID

27156057

DOI: Digital Object Identifier

PMC4919576

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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