Comparison of efficacy of pharmacological treatments for chronic idiopathic constipation: a systematic review and network meta-analysis.

Author: CamilleriMichael, ChirapongsathornSakkarin, ErwinPatricia J, MuradM Hassan, NelsonAlfred D, ShinAndrea, ValentinNelson, VijayvargiyaPriya, WangZhen

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To compare efficacy of pharmacotherapies for chronic idiopathic constipation (CIC) based on comparisons to placebo using Bayesian network meta-analysis. DATA SOURCES: We conducted searches (inception to May 2015) of MEDLINE, EMBASE, Scopus and Cochrane Central, as well as original data f...See full text at original site
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引用元:
https://doi.org/10.1136/gutjnl-2016-311835

データ提供:米国国立医学図書館(NLM)

Comparing the Effectiveness of Pharmacological Treatments for Chronic Idiopathic Constipation

Constipation, a common and often frustrating condition, can be a real drag. This study, like a meticulous cartographer mapping a vast and complex terrain, meticulously compares the efficacy of different pharmacological treatments for chronic idiopathic constipation (CIC). The researchers used a network meta-analysis to analyze data from 21 randomized controlled trials, offering a comprehensive overview of the effectiveness of various drugs compared to placebo. This study can help clinicians make informed decisions about treatment options for patients struggling with CIC.

Navigating the Landscape of Constipation Treatments: A Comparative Study

This study provides valuable insights into the effectiveness of various pharmacological treatments for CIC. The researchers found that bisacodyl, sodium picosulphate, prucalopride, and velusetrag were more effective than placebo in improving bowel movements. However, they also noted that there was no clear superiority of one drug over another in terms of overall efficacy. This indicates that finding the right treatment for each individual may require a personalized approach, taking into account factors such as individual patient characteristics and preferences.

Choosing the Right Treatment for Constipation: A Personal Journey

This study reinforces the need for a personalized approach to treating constipation. It's like discovering a hidden path in the desert – what works for one person may not work for another. The researchers found that while some drugs may be more effective for some individuals, there is no one-size-fits-all solution for constipation. This emphasizes the importance of a close doctor-patient relationship in finding the most effective treatment option.

Dr.Camel's Conclusion

This study is a valuable guide for navigating the complex landscape of constipation treatments. It reminds us that finding the right path, like finding an oasis in a desert, requires careful consideration and a personalized approach.

Date :
  1. Date Completed 2017-09-05
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

27287486

DOI: Digital Object Identifier

10.1136/gutjnl-2016-311835

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English

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