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Thyroid hormone autoantibodies: are they a better marker to detect early thyroid damage in patients with hematologic cancers receiving tyrosine kinase inhibitor or immunoregulatory drug treatments?

Author: AloisiC, AltavillaG, BenvengaS, CuzzocreaS, GallettiM, MandolfinoM, MianM, MondelloP, MondelloS, PitiniV, SantoroD, SindoniA

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigates the potential of antibodies binding thyroid hormones (thAbs) as a more reliable marker for early thyroid damage caused by antineoplastic drugs. The research suggests that thAbs may be a valuable tool for monitoring thyroid function in cancer patients undergoing potentially thyrotoxic treatment.
Paper Details　
Original Abstract of the Article :
Unlike cytotoxic agents, novel antineoplastic drugs can variably affect thyroid function and so impair patient outcomes. However, the widely used standard thyroid tests have demonstrated low sensitivity for detecting early thyroid damage that leads to dysfunction of the gland. To find a more reliabl...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900836/

データ提供：米国国立医学図書館（NLM）

Thyroid Hormone Autoantibodies: Early Detection of Thyroid Damage in Cancer Patients

This research investigates the potential of thyroid hormone autoantibodies (thAbs) as a more reliable marker for detecting early thyroid damage in patients with hematologic cancers receiving tyrosine kinase inhibitor or immunoregulatory drug treatments. The study addresses the limitations of standard thyroid tests in identifying early thyroid dysfunction, which can impact patient outcomes.

The researchers assessed the presence of thAbs in a population of cancer patients undergoing potentially thyrotoxic treatment. They aimed to determine whether thAbs could provide a more sensitive indicator of early thyroid damage compared to traditional thyroid tests.

Exploring New Markers for Early Detection

This study highlights the potential of thAbs as a more sensitive marker for detecting early thyroid damage in cancer patients undergoing specific treatments. The researchers suggest that monitoring thAbs levels could be beneficial for early intervention and improved patient outcomes.

Health and Lifestyle: Protecting Thyroid Health

Maintaining a healthy thyroid is crucial for overall well-being. While this study focuses on specific populations, it underscores the importance of regular thyroid checkups and prompt medical attention if any thyroid-related concerns arise. A balanced diet, regular exercise, and stress management are essential for supporting thyroid health.

Dr.Camel's Conclusion

This research takes us on a journey into the intricate world of thyroid function, just like a camel traversing a desert searching for a hidden oasis. The study suggests that detecting early changes in thyroid health can be crucial for improving patient outcomes. It highlights the importance of ongoing research and the need to explore new and innovative approaches to diagnose and manage thyroid conditions.

Date :
  1. Date Completed 2016-06-22
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

27330353

DOI: Digital Object Identifier

PMC4900836

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・Effective treatment of thyroid tests
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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