An update of safety of clinically used atypical antipsychotics.

Author: BuonaguroE F, CaranoA, De BartolomeisA, De BerardisD, Di GiannantonioM, FiengoA L C, FornaroM, IasevoliF, MartinottiG, MatarazzoI, MazzaM, OrsoliniL, PernaG, TomasettiC, ValcheraA, VecchiottiR, VellanteF

Paper Details 
Original Abstract of the Article :
INTRODUCTION: The atypical antipsychotic (APs) drugs have become the most widely used agents to treat a variety of psychoses because of their superiority with regard to safety and tolerability profile compared to conventional/'typical' APs. AREAS COVERED: We aimed at providing a synthesis of most c...See full text at original site
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引用元:
https://doi.org/10.1080/14740338.2016.1201475

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Atypical Antipsychotic Safety

Atypical antipsychotics (APs), a class of medications used to treat a variety of psychoses, have become widely used due to their favorable safety and tolerability profiles compared to conventional APs. This study, like a camel traversing the vast and often treacherous desert of psychopharmacology, provides a comprehensive review of the safety and tolerability profile of the most clinically used atypical APs. The authors conducted a thorough electronic search of multiple databases to synthesize the most current evidence, examining the safety and tolerability of drugs such as aripiprazole, asenapine, quetiapine, olanzapine, risperidone, paliperidone, ziprasidone, lurasidone, clozapine, amisulpride, and iloperidone. This study, like a careful map guiding a traveler across a challenging terrain, seeks to improve our understanding of the risks and benefits associated with atypical antipsychotic therapy.

Understanding the Complexities of Atypical Antipsychotic Therapy

The study's findings, like a well-placed oasis in the desert, highlight the importance of careful monitoring for metabolic side effects, such as weight gain, lipid and glycaemic imbalance, and the risk of diabetes mellitus and diabetic ketoacidosis. The research also emphasizes the need for careful baseline and periodic assessments for electrolyte imbalance, ECG abnormalities, and cardiovascular adverse effects. This study, like a compass guiding a traveler through the desert, underscores the importance of individualized treatment plans based on patient-specific factors and regular monitoring to minimize potential risks and maximize therapeutic benefits.

Finding the Right Path in Psychopharmacology

This study, like a beacon of hope in the desert, highlights the importance of understanding the risks and benefits of atypical antipsychotic therapy. The research provides valuable information for clinicians and patients alike, enabling them to make informed decisions about treatment options. By understanding the complexities of psychopharmacology, we can ensure that patients receive the most effective and safest treatments, ultimately leading to improved health outcomes.

Dr.Camel's Conclusion

This study, like a camel traversing a vast and often unforgiving desert, provides a comprehensive overview of the safety and tolerability profile of atypical antipsychotics. The findings emphasize the importance of careful monitoring for metabolic and cardiovascular side effects, highlighting the need for individualized treatment plans and regular assessments. This research, like a well-placed oasis, offers valuable insights for clinicians and patients, promoting safer and more effective psychopharmacological treatment.

Date :
  1. Date Completed 2017-02-27
  2. Date Revised 2022-04-19
Further Info :

Pubmed ID

27347638

DOI: Digital Object Identifier

10.1080/14740338.2016.1201475

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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