Minocycline combination therapy with fluvoxamine in moderate-to-severe obsessive-compulsive disorder: A placebo-controlled, double-blind, randomized trial.

Author: AbrishamiZoha, AkhondzadehShahin, EsalatmaneshSophia, NajarzadeganMohammad-Reza, RahiminejadFatemeh, SadeghiMajid, ShalbafanMohammad-Reza, ZeinoddiniAtefeh

Paper Details 
Original Abstract of the Article :
Several lines of evidence implicate glutamatergic dysfunction in the pathophysiology of obsessive-compulsive disorder (OCD), presenting this neurotransmitter as a target for the development of novel pharmacotherapy. The objective of this study was to assess the efficacy of minocycline as an augmenta...See full text at original site
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引用元:
https://doi.org/10.1111/pcn.12430

データ提供:米国国立医学図書館(NLM)

Minocycline and Fluvoxamine: A Novel Combination for OCD Treatment

The field of [psychiatry] seeks to develop effective treatments for mental health disorders, including obsessive-compulsive disorder (OCD). This study investigates the efficacy of minocycline as an augmentative agent to fluvoxamine in the treatment of OCD. The study uses [placebo-controlled, double-blind, randomized trial] to compare the effects of minocycline plus fluvoxamine, fluvoxamine alone, and placebo on OCD symptoms. The results suggest that minocycline may offer a potential benefit as an augmentative therapy to fluvoxamine in the treatment of moderate-to-severe OCD, providing a promising avenue for enhancing treatment outcomes.

Exploring New Frontiers in OCD Treatment

This study explores a novel combination therapy for treating OCD, investigating the potential benefits of minocycline as an augmentative agent to fluvoxamine. The researchers found that minocycline may enhance the therapeutic effects of fluvoxamine, offering a promising approach for improving treatment outcomes for individuals struggling with moderate-to-severe OCD. This research highlights the ongoing search for effective and innovative treatments for mental health disorders, offering hope for individuals seeking relief from OCD symptoms.

Navigating the Complexities of OCD: Finding Effective Treatment

The world of [mental health] is a challenging landscape, and finding effective treatments for disorders like OCD can feel like navigating a vast and often-uncertain desert. This study provides a glimmer of hope, suggesting that minocycline may offer a potential benefit as an augmentative therapy to fluvoxamine in the treatment of moderate-to-severe OCD. The research encourages us to continue exploring novel treatment options and to remain optimistic in the pursuit of effective solutions for individuals struggling with mental health challenges.

Dr. Camel's Conclusion

This study offers a promising new path in the journey of treating OCD. The potential of minocycline as an augmentative therapy to fluvoxamine provides a beacon of hope for individuals seeking relief from this challenging disorder. This research reminds us that the pursuit of effective treatments for mental health disorders is a continuous endeavor, requiring a commitment to exploration and innovation.

Date :
  1. Date Completed 2017-02-13
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

27488081

DOI: Digital Object Identifier

10.1111/pcn.12430

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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