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Changes in metabolic profile, iron and ferritin levels during the treatment of metastatic renal cancer - A new potential biomarker?
Author: GolčićMarin, PetkovićMarija
Original Abstract of the Article :
Metastatic renal cell carcinoma (mRCC) develops in approximately 33% of all renal cancer patients. First line treatment of mRCC includes drugs such as sunitinib, temsirolimus and pazopanib, with overall survival now reaching up to 43,6months in patients with favorable-risk metastatic disease. Severa...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.mehy.2016.07.015
データ提供:米国国立医学図書館(NLM)
Unveiling the Metabolic Secrets of Metastatic Renal Cancer
Metastatic renal cell carcinoma (mRCC) is a challenging disease, like a desert sandstorm that can quickly engulf the body. This study explores the metabolic changes that occur during the treatment of mRCC, seeking to understand how these changes can be used as potential biomarkers for treatment efficacy. The researchers embarked on a journey through the intricate landscape of mRCC, seeking to uncover the hidden clues of metabolic changes.
The study observed changes in lipid profiles, iron, and ferritin levels during mRCC treatment. The researchers hypothesize that these changes may be primarily caused by mTOR inhibition, a key pathway targeted by mRCC therapies. The study suggests that these metabolic changes may be correlated with treatment efficacy, potentially serving as biomarkers to monitor treatment response. This research sheds light on the complex metabolic landscape of mRCC, offering potential avenues for improving treatment strategies.
Metabolic Changes: A Window into mRCC Treatment
This study highlights the potential of metabolic changes, specifically in lipid profiles, iron, and ferritin levels, as potential biomarkers for monitoring treatment efficacy in mRCC. The researchers emphasize the importance of further research to validate these findings and explore their clinical implications. This research could lead to more personalized and effective treatment strategies for mRCC.
Navigating the Desert of mRCC Treatment
This study offers a valuable glimpse into the complex metabolic landscape of mRCC treatment. The researchers explore the potential of metabolic changes as biomarkers, providing a roadmap for further investigation and potentially leading to more effective treatment strategies.
Dr.Camel's Conclusion
The desert of mRCC can be a challenging journey for patients, but researchers are constantly seeking new paths to effective treatment. This study explores the potential of metabolic changes as biomarkers, potentially offering a more precise and personalized approach to mRCC treatment.
Date :
- Date Completed 2017-06-16
- Date Revised 2021-12-04
Further Info :
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