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Efficacy and Safety of Tapentadol Immediate Release Assessment in Treatment of Moderate to Severe Pain: A Systematic Review and Meta-Analysis.
Author: FengBi-Min, LiAi-Ling, WangGuo-Jun, XiaoJing-Ping, YeYun
Original Abstract of the Article :
OBJECTIVE: To assess the efficacy and safety of tapentadol IR for moderate to severe pain compared to oxycodone IR. METHODS: A search was carried out up to July 2015 for randomized controlled trials (RCTs) of tapentadol IR compared to placebo or oxycodone HCL IR 10 mg for moderate to severe pain. S...See full text at original site
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引用元:
https://doi.org/10.1093/pm/pnw154
データ提供:米国国立医学図書館(NLM)
Navigating the Pain Landscape: Tapentadol IR for Moderate to Severe Pain
This study sheds light on the use of tapentadol immediate-release (IR) for the management of moderate to severe pain, a common and debilitating symptom affecting many individuals. The researchers conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing tapentadol IR to placebo and oxycodone IR for pain relief. Their analysis revealed that tapentadol IR, at various dosages, demonstrated significant improvements in pain intensity scores compared to placebo. Importantly, tapentadol IR was found to be comparable in efficacy to oxycodone IR 10 mg, a commonly used opioid for pain management. The study also explored the safety profile of tapentadol IR, indicating a favorable side effect profile, particularly in terms of nausea and constipation, compared to oxycodone IR. These findings suggest that tapentadol IR may offer a viable alternative for managing moderate to severe pain with a potentially better safety profile.
Taming the Painful Desert: Tapentadol IR Shows Promise
The results of this study provide encouraging evidence for the use of tapentadol IR in the management of moderate to severe pain. The study's findings highlight the potential of tapentadol IR as an alternative to oxycodone IR, with a potentially better safety profile. This research may have significant implications for pain management strategies, offering patients more options for effective and safe pain relief.
A Oasis of Pain Relief in the Desert of Suffering
As a researcher, I am constantly searching for ways to alleviate human suffering. This study offers a glimmer of hope in the desert of pain management research. The discovery of a potentially safer and effective alternative to traditional opioids like oxycodone is a significant milestone in the quest for better pain relief. This study serves as a reminder that the journey through the desert of pain can lead to unexpected oases of relief and hope.
Dr.Camel's Conclusion
This study provides valuable insights into the efficacy and safety of tapentadol IR for moderate to severe pain. The findings suggest that tapentadol IR may offer a viable alternative to oxycodone IR, with a potentially better safety profile. Further research is warranted to explore the long-term efficacy and safety of tapentadol IR in a wider range of patient populations.
Date :
- Date Completed 2017-09-29
- Date Revised 2018-12-02
Further Info :
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