Experimental Glaucoma Causes Optic Nerve Head Neural Rim Tissue Compression: A Potentially Important Mechanism of Axon Injury.

Author: BurgoyneClaude F, FortuneBrad, HardinChristy, ReynaudJuan, SigalIan A, WangLin

Paper Details 
Original Abstract of the Article :
PURPOSE: We tested the hypothesis that experimental glaucoma (EG) results in greater thinning of the optic nerve head (ONH) neural rim tissue than the peripapillary retinal nerve fiber layer (RNFL) tissue. METHODS: Longitudinal spectral-domain optical coherence tomography (SDOCT) imaging of the ONH...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016000/

データ提供:米国国立医学図書館(NLM)

Glaucoma: A Tale of Optic Nerve Compression

The world of ophthalmology is a fascinating and intricate landscape, much like a desert with its own unique ecosystem. This study investigates the mechanisms of optic nerve damage in glaucoma, a condition that can lead to blindness. The study utilizes longitudinal spectral-domain optical coherence tomography (SDOCT) imaging to meticulously analyze the changes in optic nerve head (ONH) structure in nonhuman primates with experimentally induced glaucoma. The researchers found that experimental glaucoma results in a greater thinning of the ONH neural rim tissue than the peripapillary retinal nerve fiber layer (RNFL), a crucial finding for understanding the mechanisms of optic nerve damage. This research provides valuable insights into the intricate interplay of structural changes in the ONH and the progression of glaucoma.

Unraveling the Mystery of Optic Nerve Damage

This study unveils a critical mechanism of optic nerve damage in glaucoma, highlighting the importance of understanding the structural changes in the ONH. The researchers found that the compression of axon bundles within the ONH rim is a key factor in the progression of glaucoma. This research provides a new perspective on the pathophysiology of glaucoma, opening new avenues for the development of targeted therapies.

Protecting Your Vision: A Glimpse Into the Desert of Glaucoma

This study serves as a reminder of the importance of protecting our vision. It highlights the intricate mechanisms that can lead to optic nerve damage and underscores the need for early detection and treatment of glaucoma. This research offers a valuable glimpse into the complex world of glaucoma, reminding us that even seemingly subtle changes in the ONH can have significant consequences for our vision.

Dr.Camel's Conclusion

This study offers a valuable insight into the intricate mechanisms of glaucoma, a condition that can be as unforgiving as a desert storm. By understanding the processes of optic nerve compression, we can better protect our precious vision. This research is a reminder that early detection and treatment are essential for preserving our eyesight, a treasure that we should cherish like a precious oasis in the desert.

Date :
  1. Date Completed 2017-05-22
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

27564522

DOI: Digital Object Identifier

PMC5016000

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Languages

English

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