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Cisplatin and Cetuximab Treatment for Metastatic Cutaneous Squamous Cell Carcinoma: A Systematic Review.

Author: PepperJon-Paul, TrodelloCameron, WongMichael, WysongAshley

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Cetuximab demonstrated a higher complete response rate and a longer median disease-free survival than cisplatin in patients with metastatic cutaneous squamous cell carcinoma (mSCC).
Paper Details　
Original Abstract of the Article :
BACKGROUND: Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer and metastasizes in 2% to 5% of cases. OBJECTIVE: Systematic evaluation of published cases of metastatic cSCC (mSCC) treated with cisplatin or cetuximab from 1989 to 2014. MATERIALS AND METHODS: A li...See full text at original site
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引用元：
https://doi.org/10.1097/DSS.0000000000000799

データ提供：米国国立医学図書館（NLM）

Cisplatin and Cetuximab for Metastatic Cutaneous Squamous Cell Carcinoma

This research examines the effectiveness of cisplatin and cetuximab, two common chemotherapy drugs, in treating metastatic cutaneous squamous cell carcinoma (mSCC), a serious form of skin cancer. The study, conducted using a systematic review, analyzed published cases of mSCC treated with these drugs, assessing response rates and disease-free survival. The findings suggest that cetuximab may be a more effective treatment option compared to cisplatin for mSCC, highlighting the need for further research and clinical trials to confirm this observation.

Cetuximab Shows Promise in Metastatic Cutaneous Squamous Cell Carcinoma

The systematic review suggests that cetuximab may be more effective than cisplatin in treating mSCC, achieving higher complete response rates and a longer median disease-free survival. These findings highlight the potential of cetuximab as a promising therapeutic option for mSCC, but further research is needed to definitively confirm its superiority over cisplatin.

Navigating the Landscape of Skin Cancer Treatment

The research underscores the importance of ongoing research and development of new and effective treatments for mSCC. The study highlights the potential of cetuximab as a promising therapeutic option, but further research and clinical trials are necessary to establish definitive guidelines for its use and to compare its efficacy with other treatment modalities. It’s like exploring a vast desert landscape, seeking out the most effective paths to treat this challenging form of skin cancer.

Dr. Camel's Conclusion

This research explores the potential of cetuximab as a promising treatment for mSCC, offering hope for improved outcomes for patients battling this aggressive form of skin cancer. Just as a camel navigates the desert landscape with resilience and determination, we must continue to explore new avenues for treating this serious condition and improving the lives of those affected.

Date :
  1. Date Completed 2017-04-07
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

27618393

DOI: Digital Object Identifier

10.1097/DSS.0000000000000799

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Article Analysis
・Effective treatment of skin cancer
SNS
PICO Info
in preparation
Languages

English

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