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Effects of a switch from tenofovir- to abacavir-based antiretroviral therapy, with or without atazanavir, on renal function.
Author: DahlbyJulia S, GuillemiSilvia A, HarrisMarianne, HoggRobert S, HullMark W, LimaViviane Dias, LingSean H, MontanerJulio S, WerbRonald, YipBenita, ZhangWendy
Original Abstract of the Article :
INTRODUCTION: Tenofovir disoproxil fumarate (TDF)-associated renal dysfunction may abate when TDF is replaced with abacavir (ABC). The extent to which the third drug atazanavir contributes to renal dysfunction is unclear. METHODS: A retrospective analysis was conducted on adults who had plasma vira...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元：
https://doi.org/10.7448/IAS.19.1.20995
データ提供：米国国立医学図書館（NLM）
Effects of a Switch from Tenofovir- to Abacavir-Based Antiretroviral Therapy, with or Without Atazanavir, on Renal Function
As a researcher, I am always fascinated by the intricate interplay between medications and the human body. This study focuses on the potential impact of switching from tenofovir-based antiretroviral therapy to abacavir-based therapy on renal function in HIV-positive individuals.
The researchers conducted a retrospective analysis of adults who switched from tenofovir-based antiretroviral therapy to abacavir-based therapy while maintaining viral suppression. They found that switching to abacavir-based therapy resulted in improvements in renal function, regardless of whether or not the patients were also receiving atazanavir. This study provides valuable insights into the potential benefits of switching to abacavir-based therapy for HIV-positive individuals.
A Potential Benefit for HIV-Positive Individuals with Renal Dysfunction
This study suggests that switching from tenofovir-based antiretroviral therapy to abacavir-based therapy may be beneficial for HIV-positive individuals with renal dysfunction. The findings indicate that this switch can lead to improvements in renal function, potentially improving overall health and well-being. This research offers hope for HIV-positive individuals who are struggling with tenofovir-associated renal dysfunction.
Understanding the Impact of Antiretroviral Therapy on Renal Function
This study highlights the importance of understanding the impact of antiretroviral therapy on renal function. While antiretroviral therapy has been instrumental in improving the lives of HIV-positive individuals, it is essential to be aware of potential side effects, such as renal dysfunction. This research provides valuable information for healthcare professionals who are managing HIV-positive individuals and need to make informed decisions about their treatment plans.
Dr.Camel's Conclusion
Just as a camel needs to adapt to the harsh desert environment, HIV-positive individuals need to adapt to the complexities of their treatment regimens. This study offers valuable insights into the potential benefits of switching to abacavir-based therapy, highlighting the importance of individualized care and careful monitoring of renal function.
Date :
- Date Completed 2017-08-30
- Date Revised 2018-12-02
Further Info :
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