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Effects of Lorcaserin on Cocaine and Methamphetamine Self-Administration and Reinstatement of Responding Previously Maintained by Cocaine in Rhesus Monkeys.
Author: CollinsGregory T, FranceCharles P, GerakLisa R
Original Abstract of the Article :
Stimulant abuse is a serious public health issue for which there is no effective pharmacotherapy. The serotonin<sub>2C</sub> [5-hydroxytryptamine<sub>2C</sub> (5-HT<sub>2C</sub>)] receptor agonist lorcaserin decreases some abuse-related effects of cocaine in monkeys and might be useful for treating ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118643/
データ提供:米国国立医学図書館(NLM)
Lorcaserin: A Potential Weapon Against Stimulant Abuse
The desert of substance abuse is a treacherous landscape, filled with hidden dangers and the constant threat of relapse. Like a mirage that promises relief but ultimately leads to disappointment, stimulant abuse can trap individuals in a cycle of addiction.This study delves into the desert of addiction research, exploring the potential of lorcaserin, a serotonin2C receptor agonist, to combat the abuse of cocaine and methamphetamine. The researchers, like skilled desert explorers, meticulously conducted their experiments in rhesus monkeys, examining the effects of lorcaserin on drug self-administration and reinstatement of drug-seeking behavior.
The study's findings, like a refreshing oasis in the desert, suggest that lorcaserin may hold promise for the treatment of stimulant abuse. The researchers observed that lorcaserin effectively reduced cocaine and methamphetamine self-administration and also decreased cocaine-induced reinstatement of drug-seeking behavior. These results, like a beacon in the desert, offer hope for those struggling with stimulant addiction. The researchers emphasize that further research is necessary to fully understand the potential of lorcaserin and to determine its effectiveness in humans.
Fighting the Sandstorm of Addiction
This study provides valuable insight into the desert of stimulant abuse, highlighting the potential of lorcaserin as a weapon against this insidious foe. The researchers' findings, like a map leading to a hidden oasis, offer hope for those struggling with addiction. The study underscores the importance of continuing research into new and effective treatments for stimulant abuse, as we strive to create a brighter future for those battling this challenging condition.Navigating the Desert of Addiction Recovery
As we navigate the desert of addiction recovery, it's important to have hope and to know that effective treatment options are available. This study reminds us that scientific research continues to explore new and promising avenues for addressing the challenges of substance abuse. Remember, the desert may be vast and unforgiving, but with determination and the right tools, we can find our way to a brighter future.Dr. Camel's Conclusion
This study offers a beacon of hope in the desert of stimulant abuse, suggesting that lorcaserin may hold promise for the treatment of cocaine and methamphetamine addiction. The researchers' findings, like a refreshing oasis, offer a valuable resource for those seeking to overcome the challenges of addiction. As we continue to explore this complex and challenging landscape, we can take heart in the knowledge that scientific research is constantly searching for new solutions.Date :
- Date Completed 2017-05-16
- Date Revised 2018-11-13
Further Info :
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