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Impact of Statin Therapy on Plasma Vitamin D Levels: A Systematic Review and Meta-Analysis.
Author: Della CorteClaudia, FerrettiGianna, NobiliValerio, ReinerZeljko, SahebkarAmirhossein, Simental-MendiaLuis E
Original Abstract of the Article :
BACKGROUND: During recent years, treatment with statins has been suggested to induce several effect on bone status and vitamin D metabolism, interpreted as statins pleiotropic effects. Actually, the available data are not conclusive and the characteristics of this association remains unclear. AIM: ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/27719645
データ提供:米国国立医学図書館(NLM)
Statins and Vitamin D: A Complex Relationship
This study examines the potential impact of statin therapy on plasma vitamin D levels, exploring the complex relationship between these two commonly prescribed medications. They conducted a systematic review and meta-analysis to investigate the association between statin use and vitamin D levels based on existing data from randomized controlled trials and observational studies.No Definitive Evidence of a Link
The meta-analysis found no significant effect of statin therapy on plasma vitamin D levels. The authors highlighted that the data available was limited, and further well-designed trials are needed to definitively determine whether any association exists between statin use and vitamin D levels.Monitoring Vitamin D Levels in Statin Users
While this study suggests that statin therapy does not significantly impact vitamin D levels, it's still important to monitor vitamin D levels in individuals taking statins. This is particularly relevant for individuals with existing vitamin D deficiency, as they may require supplementation to maintain adequate levels. Regular monitoring and personalized recommendations based on individual needs are crucial for optimizing health outcomes.Dr.Camel's Conclusion
This study is like a desert oasis—it offers a refreshing perspective on the relationship between statins and vitamin D. While the study suggests that statins don't have a significant impact on vitamin D levels, it's still a good practice to monitor these levels in patients taking statins, especially those with a history of vitamin D deficiency. It reminds us that maintaining overall health requires a holistic approach, considering the interplay between various factors, including medications, diet, and lifestyle.Date :
- Date Completed 2018-02-19
- Date Revised 2022-04-08
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