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Pharmacogenomics and adverse drug reactions: Primetime and not ready for primetime tests.

Author: KhanDavid A

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This review focuses on pharmacogenetics and pharmacogenomics and their role in reducing adverse drug reactions (ADRs), particularly those caused by drug hypersensitivity reactions. It highlights the importance of genetic testing for specific drugs and ADRs.
Paper Details　
Original Abstract of the Article :
Adverse drug reactions (ADRs) are a relatively common cause of morbidity and mortality. Many factors can contribute to ADRs, including genetics. The degree to which genetics contributes to ADRs is not entirely clear and varies by drug, as well as the type of ADR. Pharmacogenetics and, more recently,...See full text at original site
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引用元：
https://doi.org/10.1016/j.jaci.2016.08.002

データ提供：米国国立医学図書館（NLM）

Pharmacogenetics: A Personalized Approach to Drug Therapy

Adverse drug reactions (ADRs) are a common concern in medicine, often caused by genetic variations. This research explores the growing field of pharmacogenetics, a field that aims to personalize drug therapy based on individual genetic profiles. The study examines the potential of pharmacogenetic testing to reduce ADRs, particularly those related to drug hypersensitivity reactions.

Tailoring Treatment: Navigating the Genetic Desert

This study emphasizes the importance of considering individual genetic variations when prescribing medications. Just as a traveler needs to adapt to the unique characteristics of each desert landscape, clinicians must understand the genetic landscape of their patients to optimize drug therapy. The study highlights the potential of pharmacogenetic testing to minimize ADRs and improve patient outcomes.

A New Era of Personalized Medicine

This research offers a glimpse into the future of medicine, where treatments are tailored to the individual. Imagine a world where medications are as unique as the fingerprints of their recipients. Pharmacogenetics holds the promise of a more personalized and effective approach to drug therapy, minimizing ADRs and improving patient safety.

Dr.Camel's Conclusion

This research underscores the importance of embracing pharmacogenetics and personalized medicine to advance patient care. Like a camel adapting to the changing sands of the desert, clinicians must adapt their approaches to drug therapy to accommodate the unique genetic profiles of their patients. The field of pharmacogenetics offers a promising path toward a future of safer and more effective medicine.

Date :
  1. Date Completed 2017-07-05
  2. Date Revised 2018-09-19
Further Info :

Pubmed ID

27720019

DOI: Digital Object Identifier

10.1016/j.jaci.2016.08.002

SNS
PICO Info
in preparation
Languages

English

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