Haloperidol plus promethazine for psychosis-induced aggression.

Author: AlexanderJacob, AllenMichael H, GandhiPinky, HufGisele

Paper Details 
Original Abstract of the Article :
BACKGROUND: Health services often manage agitated or violent people, and such behaviour is particularly prevalent in emergency psychiatric services (10%). The drugs used in such situations should ensure that the person becomes calm swiftly and safely. OBJECTIVES: To examine whether haloperidol plus...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464403/

データ提供:米国国立医学図書館(NLM)

Haloperidol Plus Promethazine: A Winning Combination for Psychosis-Induced Aggression?

The world of mental health is a vast desert, and navigating its complexities is a challenge, especially when dealing with aggression. This research explores the effectiveness of haloperidol plus promethazine as a treatment for psychosis-induced aggression. This research employed a systematic review and meta-analysis, a process that helps us see the bigger picture in a way similar to how a camel can see the entire desert from a high dune. The authors reviewed six randomized controlled trials (RCTs) involving 1367 participants, looking at the effectiveness of the combination compared to other treatments. Their findings suggest that haloperidol plus promethazine is more effective than haloperidol alone, and might be a viable option compared to other treatments like olanzapine and ziprasidone.

Haloperidol Plus Promethazine: A More Effective Treatment

The results of this review show that haloperidol plus promethazine was more effective than haloperidol alone in calming patients with psychosis-induced aggression. This combination also seemed to cause less sedation compared to other treatments. This is significant because it could help ensure patients remain alert and can participate in their own treatment. This is similar to how the desert can be both beautiful and dangerous, and we need the right tools to navigate it effectively. Haloperidol alone can sometimes be like a desert mirage, tempting but ultimately unreliable. Combining haloperidol with promethazine can provide the right balance, like a camel carrying its supplies across the desert.

Navigating the Desert of Aggression

This research highlights the importance of careful medication selection in managing psychosis-induced aggression. The combination of haloperidol plus promethazine offers a promising alternative to other treatments, with a potential benefit of reduced sedation. Understanding the dynamics of aggression and finding effective solutions is a continuous journey, just like a camel navigating the endless desert. We must stay vigilant and continue to seek better treatments, ensuring that the desert of mental health becomes a more manageable landscape for everyone.

Dr.Camel's Conclusion

The combination of haloperidol plus promethazine appears to be a winning formula for managing psychosis-induced aggression. This research provides valuable insights into the effectiveness of this treatment compared to other options. The findings are like a refreshing oasis in the desert of mental health, offering hope for more effective and safe treatments for patients facing challenging situations.

Date :
  1. Date Completed 2017-01-10
  2. Date Revised 2023-09-19
Further Info :

Pubmed ID

27885664

DOI: Digital Object Identifier

PMC6464403

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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