Can drugs induce or aggravate sleep apneas? A case-noncase study in VigiBase<sup>&#174;</sup> , the WHO pharmacovigilance database.

Author: BagheriHaleh, BeneventJustine, Bondon-GuittonEmmanuelle, ChebaneLeila, DurrieuGeneviève, LinselleMélanie, MontastrucFrançois, MontastrucJean-Louis, MoulisFlorence, RousseauVanessa, SommetAgnès

Paper Details 
Original Abstract of the Article :
The potential favorizing role of drugs in sleep apnea syndrome (SAS) is unknown. This study investigates drugs associated with SAS in a pharmacovigilance database. SAS recorded as adverse drug reactions (ADRs) in VigiBase<sup>&#174;</sup> , the WHO pharmacovigilance database (more than 11 million re...See full text at original site
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引用元:
https://doi.org/10.1111/fcp.12264

データ提供:米国国立医学図書館(NLM)

Exploring the Potential of Drugs to Induce or Aggravate Sleep Apneas

Sleep apnea syndrome (SAS) is a prevalent condition that can have significant impacts on sleep quality, overall health, and even mortality. This study explores the potential role of medications in inducing or aggravating SAS. The researchers analyzed data from a large pharmacovigilance database, examining the frequency of SAS reports associated with various medications. This research sheds light on the complex interplay between medications and sleep disorders.

Medications Potentially Linked to Sleep Apnea Syndrome

The study identified several medications, including sodium oxybate, rofecoxib, quetiapine, and clozapine, as well as drug classes like coxibs, antipsychotics, benzodiazepines, and opium alkaloids, that may be associated with SAS. This finding suggests that clinicians should consider the potential impact of medications on sleep disorders when treating patients with SAS.

Navigating the Potential Impact of Medications on Sleep

This study emphasizes the importance of considering medication use when evaluating and managing SAS. Like a camel carefully navigating a treacherous path through the desert, physicians must be mindful of the potential impact of medications on their patients' sleep health.

Dr.Camel's Conclusion

This study underscores the complex relationship between medications and sleep disorders, particularly SAS. By understanding the potential impact of medications on sleep, clinicians can better manage SAS and optimize patient outcomes.

Date :
  1. Date Completed 2018-02-27
  2. Date Revised 2018-02-27
Further Info :

Pubmed ID

28036099

DOI: Digital Object Identifier

10.1111/fcp.12264

Related Literature

SNS
PICO Info
in preparation
Languages

English

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