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A comparison of the effects of oral vs. intravenous hydration on subclinical acute kidney injury in living kidney donors: a protocol of a randomised controlled trial.

Author: AitkenEmma, ClancyMarc, GhitaRyan, MackinnonShona

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This research discusses the use of preoperative intravenous fluids to minimize the risk of acute kidney injury in living kidney donors undergoing laparoscopic donor nephrectomy. The study explores the potential benefits of hydration for preserving donor renal function.
Paper Details　
Original Abstract of the Article :
Optimal treatment for established renal failure is living donor kidney transplantation. However this pathway exposes healthy individuals to significant reduction in nephron mass via major surgical procedure. Laparoscopic donor nephrectomy is now the most common method for live donor transplantation,...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244581/

データ提供：米国国立医学図書館（NLM）

Optimizing Hydration Strategies for Living Kidney Donors

Living donor kidney transplantation is a life-saving procedure for individuals with kidney failure. This study examines the potential benefits of different hydration strategies for living kidney donors, focusing on the impact of hydration on subclinical acute kidney injury (AKI).

The researchers propose a randomized controlled trial to compare the effects of oral and intravenous hydration on the development of subclinical AKI in living kidney donors. The hypothesis is that intravenous hydration, particularly preoperatively, may help to protect the kidneys from hemodynamic stress during the laparoscopic donor nephrectomy procedure.

Improving Kidney Function and Transplant Outcomes

The study aims to provide evidence-based recommendations on the optimal hydration strategy for living kidney donors, potentially leading to improved kidney function and transplant outcomes.

The Importance of Donor Care

The study highlights the importance of providing comprehensive care to living kidney donors, considering the potential risks and benefits of different interventions.

Dr.Camel's Conclusion

The world of kidney transplantation is a complex desert landscape, where the journey to a successful transplant requires careful navigation. This study aims to provide a roadmap for optimizing hydration strategies for living kidney donors, ensuring a smooth and safe journey for these selfless individuals.

Date :
  1. Date Completed 2018-02-21
  2. Date Revised 2023-11-12
Further Info :

Pubmed ID

28103829

DOI: Digital Object Identifier

PMC5244581

SNS
PICO Info
in preparation
Languages

English

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