[Investigation of Administration Technique of Regorafenib in Our Center].

Author: DannoKatsuki, FujitaniKazumasa, IwaseKazuhiro, KitagawaAkihiro, KubotaMasaru, MatsudaChu, MiyazakiSusumu, MotooriMasaaki, NakatsukaRie, NishimuraMasashige, TakagiMari

Paper Details 
Original Abstract of the Article :
Regorafenib is an oral multikinase inhibitor; the CORRECTtrial evaluated its efficacy in patients with metastatic colorectal cancer following disease progression with standard therapies. However, regorafenib has toxicities that develop quickly. Few studies have reported the safe dose and usage of re...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/28174379

データ提供:米国国立医学図書館(NLM)

Optimizing Regorafenib Administration

Regorafenib, a multikinase inhibitor used in the treatment of metastatic colorectal cancer, can be a powerful tool for managing the disease. However, its use can be challenging due to potential toxicities. This study examines the safe dose and administration technique of regorafenib in Japanese patients.

The researchers investigated the side effects and efficacy of regorafenib in a group of patients with metastatic colorectal cancer. They compared two different dosing regimens, one starting with a higher dose and the other with a lower dose that was gradually increased.

Their findings suggest that starting with a lower dose of regorafenib and gradually increasing it, as the patient's tolerance permits, may be a safer approach. This strategy allows for longer treatment courses and a higher total dose of regorafenib, potentially improving overall survival.

Individualized Treatment for Cancer Patients

This research underscores the importance of individualizing cancer treatment based on the patient's unique characteristics. By carefully managing dosage and adjusting it according to the patient's response, we can maximize the benefits of regorafenib while minimizing potential side effects.

Finding the Right Path for Cancer Treatment

The study highlights the complexities of cancer treatment and the need for ongoing monitoring and adjustments. Just as a camel carefully navigates a changing desert landscape, healthcare professionals must be adaptable in their approach to cancer treatment, striving for optimal outcomes for each patient.

Dr.Camel's Conclusion

This research emphasizes the importance of finding the right dosage and administration technique for each cancer patient. Just as a camel must carefully choose its path through the desert, healthcare professionals must personalize cancer treatment to ensure the best possible outcomes.

Date :
  1. Date Completed 2017-03-01
  2. Date Revised 2017-03-02
Further Info :

Pubmed ID

28174379

DOI: Digital Object Identifier

28174379

Related Literature

SNS
PICO Info
in preparation
Languages

Japanese

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