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Is there a role for thioguanine therapy in IBD in 2017 and beyond?

Author: BlakerPaul A, SparrowMiles P, TaylorKirstin M, WardMark G

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Thioguanine is an alternative thiopurine that has shown efficacy in inflammatory bowel disease. This study aims to outline the rational use of thioguanine, including safety monitoring, with particular regard to hepatotoxicity.
Paper Details　
Original Abstract of the Article :
Conventional thiopurines are effective for the maintenance of remission of Crohn's disease and ulcerative colitis, however, up to half of patients are intolerant or unresponsive to these medications. Thioguanine is an alternative thiopurine that has shown efficacy in inflammatory bowel disease, and ...See full text at original site
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引用元：
https://doi.org/10.1080/17474124.2017.1294062

データ提供：米国国立医学図書館（NLM）

Thioguanine's Role in Inflammatory Bowel Disease: A New Path for Treatment

Inflammatory bowel disease (IBD), a chronic and debilitating condition, requires long-term management. This study examines the potential of thioguanine, a medication, as an alternative treatment for IBD. The researchers discuss the effectiveness and safety of thioguanine, highlighting its potential advantages over conventional medications.

A New Oasis for IBD Treatment

The study suggests that thioguanine might be a valuable alternative for patients with IBD who are intolerant or unresponsive to conventional thiopurine medications. It offers a potential solution for those struggling with side effects or lack of effectiveness with traditional treatments.

Navigating IBD Treatment: Choosing the Right Path

This research provides valuable information for healthcare professionals and patients alike. It emphasizes the importance of considering thioguanine as a potential treatment option for IBD, while also acknowledging the need for careful monitoring and management of potential side effects.

Dr.Camel's Conclusion

This study offers a new path for treating IBD, much like discovering a hidden oasis in a vast desert. It reminds us that the search for effective treatments is a constant journey, requiring exploration and adaptation to find the right solution for each individual.

Date :
  1. Date Completed 2017-10-23
  2. Date Revised 2017-10-23
Further Info :

Pubmed ID

28276819

DOI: Digital Object Identifier

10.1080/17474124.2017.1294062

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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