Statin-Associated Autoimmune Myopathy: A Systematic Review of 100 Cases.

Author: DonatoAnthony, LohaniSaroj, NazirSalik, PoudelDilliram, TachamoNiranjan

Paper Details 
Original Abstract of the Article :
Statins are a group of drugs that reduce the levels of triglycerides and cholesterol in blood by inhibiting HMG-CoA reductase, an enzyme involved in rate limiting step in cholesterol synthesis. About 2-20% patients on statins develop toxic myopathies, which usually resolve on discontinuation of stat...See full text at original site
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引用元:
https://doi.org/10.1097/RHU.0000000000000497

データ提供:米国国立医学図書館(NLM)

Statin-Associated Autoimmune Myopathy

In the vast and intricate world of medicine, we often encounter unintended consequences of even the most beneficial therapies. This systematic review delves into a specific adverse effect associated with statins, a class of drugs widely used to lower cholesterol levels. The review examines a rare but serious condition known as statin-associated autoimmune myopathy, a potentially debilitating muscle disorder.

The Complexities of Statin-Associated Myopathy

The review compiles data from 100 cases of statin-associated autoimmune myopathy, shedding light on its clinical presentation, diagnostic challenges, and treatment approaches. It highlights the importance of recognizing this condition as a potential adverse effect of statin therapy, especially in cases of persistent muscle weakness or unexplained myalgia.

Navigating the Risks and Benefits of Statin Therapy

This systematic review serves as a reminder that even the most effective therapies can have unintended consequences. It underscores the importance of careful patient monitoring and a thorough understanding of potential adverse effects. It's like navigating a desert landscape - while the journey may offer many rewards, it's important to be aware of potential hazards and to take necessary precautions.

Dr.Camel's Conclusion

This systematic review reminds us that the desert of medical knowledge is vast and ever-evolving. While statins have proven beneficial in managing cholesterol levels, it's crucial to acknowledge potential adverse effects like statin-associated autoimmune myopathy. It's a reminder that navigating the complex world of medical treatment requires careful consideration, personalized approaches, and a constant pursuit of understanding. As a wise old camel, I encourage you to stay informed and to consult with your healthcare provider about potential risks and benefits associated with any medication you are taking.

Date :
  1. Date Completed 2017-11-21
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28277343

DOI: Digital Object Identifier

10.1097/RHU.0000000000000497

Related Literature

SNS
PICO Info
in preparation
Languages

English

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