Oral anticoagulants for primary prevention, treatment and secondary prevention of venous thromboembolic disease, and for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis and cost-effectiveness analysis.

Author: BodaliaPritesh N, BrydenPeter A, CaldwellDeborah M, DaviesPhilippa A, DiasSofia, EatonDiane, HigginsJulian Pt, HingoraniAroon D, HollingworthWill, López-LópezJose A, OkoliGeorge N, SalisburyChris, SavovićJelena, SofatReecha, Stephens-BoalAnnya, SterneJonathan Ac, ThomHoward Hz, WeltonNicky J

Paper Details 
Original Abstract of the Article :
Warfarin is effective for stroke prevention in atrial fibrillation (AF), but anticoagulation is underused in clinical care. The risk of venous thromboembolic disease during hospitalisation can be reduced by low-molecular-weight heparin (LMWH): warfarin is the most frequently prescribed anticoagulant...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366855/

データ提供:米国国立医学図書館(NLM)

Oral Anticoagulants for Venous Thromboembolism and Atrial Fibrillation: A Comprehensive Review

The prevention and treatment of blood clots, like navigating the treacherous sands of a desert, requires careful consideration of various factors. This research provides a comprehensive review of oral anticoagulants, medications that help prevent blood clots, for various conditions, including venous thromboembolism (VTE) and atrial fibrillation (AF). The authors delve into the effectiveness and safety of different anticoagulants, including warfarin, low-molecular-weight heparin (LMWH), and novel oral anticoagulants (NOACs).

Comparing Anticoagulant Options

This study, like a desert expedition meticulously mapping a vast terrain, compares the effectiveness and cost-effectiveness of different oral anticoagulants. The authors highlight the effectiveness of warfarin in preventing stroke in patients with atrial fibrillation but also acknowledge the challenges of managing warfarin therapy due to its narrow therapeutic window and the need for regular monitoring. They also explore the advantages of NOACs, which offer more predictable dosing and a quicker onset and offset of action. The results emphasize the need for careful individualization of anticoagulant therapy based on patient characteristics and specific medical conditions.

Navigating Anticoagulant Therapy

As you navigate the desert of blood clot prevention and treatment, remember that your doctor is your trusted guide. Be sure to discuss your medical history and any potential risks or concerns with your doctor to ensure you receive the most appropriate anticoagulant therapy. Like a wise camel, be proactive in managing your health and seeking professional guidance when needed.

Dr.Camel's Conclusion

This comprehensive review provides valuable insights into the complex world of oral anticoagulants. By understanding the different options available, healthcare professionals can make informed decisions about the best treatment approach for each individual. It's a reminder that even in the arid landscape of blood clotting disorders, we have effective tools to help patients navigate these challenges and live healthy lives.

Date :
  1. Date Completed 2018-02-28
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

28279251

DOI: Digital Object Identifier

PMC5366855

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Languages

English

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