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A Phase 2, Multicenter, Double-Blind, Randomized, Vehicle Controlled Clinical Study to Assess the Safety and Efficacy of a Halobetasol/Tazarotene Fixed Combination in the Treatment of Plaque Psoriasis.

Author: AlexanderBinu J, GoldLinda Stein, LebwohlMark G, PariserDavid M, PillaiRadhakrishnan, SugarmanJeffrey L

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical Trial, Phase IIA Phase II trial is a trial that further evaluates the efficacy and safety of a new drug or treatment, whose safety has been confirmed to some extent in a Phase I trial, in a small number of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

Psoriasis is a chronic skin condition that varies in severity. Topical corticosteroids are a common treatment, but long-term use can be a concern. Combining a corticosteroid with tazarotene might improve psoriasis symptoms while using a lower dose of the corticosteroid, potentially making treatment safer.
Paper Details　
Original Abstract of the Article :
<p>BACKGROUND: Psoriasis is a chronic, immune-mediated disease that varies widely in its clinical expression. Treatment options focus on relieving symptoms, reducing inflammation, induration, and scaling, and controlling the extent of the disease. Topical corticosteroids are the mainstay of treatmen...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/28301614

データ提供：米国国立医学図書館（NLM）

Xeroform: Examining the Antimicrobial Spectrum

The field of [wound care] is constantly seeking [effective and safe treatments for wounds]. This study investigates the [antimicrobial spectrum] of [Xeroform], a [petrolatum-based gauze containing bismuth tribromophenate]. The researchers employed [in-vitro zone-of-inhibition methodology] to assess the [antimicrobial activity] of Xeroform against [common burn pathogens]. The study's findings suggest that Xeroform exhibits [significant antimicrobial activity] against a range of [bacteria and fungi], highlighting its potential for [wound management] in burn and plastic surgery.

Xeroform: A Valuable Tool for Wound Care

This study provides valuable insights into the [antimicrobial properties] of Xeroform, a widely used [wound dressing] in burn and plastic surgery. The researchers' findings confirm its [effectiveness against a broad range of pathogens], making it a [valuable tool for preventing infection] and promoting wound healing.

The Desert of Wound Healing: Seeking Effective Treatments

This research reminds us of the [importance of wound care] in promoting healing and preventing complications. It's like navigating a desert landscape, where each step needs careful attention to avoid getting lost in the dangers of infection. By understanding the [antimicrobial properties of Xeroform], we can better equip ourselves to [effectively manage wounds] and promote healing.

Dr. Camel's Conclusion

This study confirms the antimicrobial properties of Xeroform, a valuable tool for wound management. It's like discovering a hidden oasis in the desert of wound care: a source of protection against the dangers of infection and a vital resource for promoting healing.

Date :
  1. Date Completed 2017-09-14
  2. Date Revised 2017-09-14
Further Info :

Pubmed ID

28301614

DOI: Digital Object Identifier

S1545961617P0197X

Related Literature

Article Analysis
・Effective treatment of psoriasis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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