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Suvorexant for the treatment of primary insomnia: A systematic review and meta-analysis.

Author: KuriyamaAkira, TabataHiromitsu

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This systematic review and meta-analysis assessed the efficacy and safety of suvorexant, a dual orexin receptor agonist, for the treatment of primary insomnia. Suvorexant is approved for the treatment of insomnia in the United States and Japan.
Paper Details　
Original Abstract of the Article :
Suvorexant is a dual orexin receptor agonist and is currently approved for the treatment of insomnia in the United States and Japan. We conducted a systematic review and meta-analysis to assess the efficacy and safety of suvorexant for the treatment of primary insomnia. We searched PubMed, EMBASE, a...See full text at original site
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引用元：
https://doi.org/10.1016/j.smrv.2016.09.004

データ提供：米国国立医学図書館（NLM）

Suvorexant: A Novel Approach to Insomnia Treatment

Insomnia, a sleep disorder that leaves people feeling tired and restless, is like a long, hot desert night that makes it difficult to find rest. Traditional treatments for insomnia often focus on sleep hygiene and relaxation techniques, but new medications are being developed to address this common issue.

A Dual Orexin Receptor Agonist: Suvorexant

This systematic review and meta-analysis assesses the efficacy and safety of suvorexant, a dual orexin receptor agonist, for the treatment of primary insomnia. The analysis of four randomized trials involving 3076 patients found that suvorexant was associated with significant improvements in sleep parameters, such as time to sleep onset and total sleep time.

Hope for a More Restful Night

The study suggests that suvorexant could be a promising treatment option for individuals struggling with insomnia. However, it’s important to note that suvorexant can cause side effects, such as somnolence, fatigue, and abnormal dreams.

Dr.Camel's Conclusion

The study provides insights into the potential of suvorexant to improve sleep quality for those with insomnia. As with any new medication, it’s crucial to weigh the potential benefits against the risks and consult with a healthcare professional to determine the best treatment plan.

Date :
  1. Date Completed 2018-06-04
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28365447

DOI: Digital Object Identifier

10.1016/j.smrv.2016.09.004

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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