Safety and effectiveness of oral propranolol for infantile hemangiomas started before 5 weeks and after 5 months of age: an Italian multicenter experience.

Author: BertiIrene, BoccalettiValeria, CarnevaleClaudia, CutroneMario, DalmontePietro, DiociaiutiAndrea, El HachemMaya, GesualdoFrancesco, GrecoAntonella, NeriIria, OrangesTeresa, PorceddaGiulio, VercellinoNadia

Paper Details 
Original Abstract of the Article :
Despite not being licensed for the treatment of infantile hemangiomas (IH) in infants younger than 5 weeks or older than 5 months, propranolol is often used in these age groups to prevent or to treat potentially severe complications. The objective of the present study was to review the experience of...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395924/

データ提供:米国国立医学図書館(NLM)

Propranolol for infantile hemangiomas: A desert of uncertainty

This study explores the use of propranolol, a medication commonly used to treat high blood pressure, for the treatment of infantile hemangiomas, which are birthmarks that can be problematic. While propranolol is often used for these conditions, it's not yet approved for infants younger than five weeks or older than five months. This study aims to shed light on the safety and effectiveness of propranolol in these age groups, navigating the desert of uncertainty surrounding its use in young infants.

Charting the course: A multi-center review of propranolol treatment

This study is like a collaborative effort of many camel caravans traversing the desert of infantile hemangiomas. Eight Italian pediatric and dermatologic centers pooled their data to evaluate the use of propranolol in infants outside of the approved age range. This collaborative approach provides a more comprehensive view of the treatment landscape, helping to guide future research and clinical practice.

A cautious approach: Understanding the potential benefits and risks

This study emphasizes the need for careful consideration when using propranolol for infantile hemangiomas in infants outside of the approved age range. It's like exploring a new route through the desert – while there may be potential benefits, there are also risks that need to be understood and managed. The study aims to provide valuable information for physicians to make informed decisions regarding the use of propranolol in these cases.

Dr.Camel's Conclusion

This study is like a guidepost in the desert, providing valuable insights into the use of propranolol for infantile hemangiomas in infants outside of the approved age range. While propranolol holds promise for treatment, it's crucial to proceed with caution and weigh the potential benefits against the risks, ensuring the safety and well-being of these delicate patients. As I, Dr. Camel, have learned from my journeys across the desert, knowledge is power, and it's essential for navigating the complex landscape of healthcare.

Date :
  1. Date Completed 2018-02-28
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

28424095

DOI: Digital Object Identifier

PMC5395924

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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