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Efficacy of Lomitapide in the Treatment of Familial Homozygous Hypercholesterolemia: Results of a Real-World Clinical Experience in Italy.

Author: ArcaMarcello, AvernaMaurizio, BigazziFederico, BonomoKatia, BucciMarco, CalabresiLaura, CalabròPaolo, CefalùAngelo Baldassare, D'ErasmoLaura, GiammancoAntonina, MeddePaolo, NataleFrancesco, NotoDavide, PavanelloChiara, PintusPaolo, SabbàCarlo, SampietroTiziana, SbranaFrancesco, SileoFulvio, SirtoriCesare, SuppressaPatrizia, VignaGiovanni Battista

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study evaluated the benefits of lomitapide in patients with homozygous familial hypercholesterolaemia (HoFH) who were already receiving standard clinical care.
Paper Details　
Original Abstract of the Article :
Homozygous familial hypercholesterolaemia (HoFH) is a rare form of inherited dyslipidemia resistant to conventional cholesterol-lowering medications so that lipoprotein apheresis (LA) is usually required. Lomitapide has been approved for the treatment of HoFH. The aim of this study was to evaluate t...See full text at original site
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引用元：
https://doi.org/10.1007/s12325-017-0531-x

データ提供：米国国立医学図書館（NLM）

Lomitapide: A Novel Treatment for a Rare Lipid Disorder

Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by extremely high cholesterol levels, making it difficult to manage with conventional treatments. This study explores the effectiveness of lomitapide, a drug specifically designed to treat HoFH, in a real-world clinical setting. The study aimed to evaluate the benefits of lomitapide in patients with HoFH, considering the challenges of treating this complex condition.

Lomitapide: A Promising Treatment for a Challenging Condition

The study found that lomitapide was effective in reducing cholesterol levels in HoFH patients. The researchers believe that lomitapide could be a valuable addition to the treatment arsenal for HoFH, potentially reducing the need for lipoprotein apheresis, a more invasive procedure.

Health Considerations and Lifestyle Changes

This study offers hope for individuals with HoFH, highlighting the potential of lomitapide to improve their lipid profiles and overall health. It's important to consult with a healthcare professional to determine if lomitapide is appropriate for your individual needs and to discuss any potential side effects.

Dr. Camel's Conclusion

Just as a camel can navigate a desert landscape by utilizing its unique adaptations, researchers are constantly seeking new ways to address rare and challenging medical conditions. This study highlights the potential of lomitapide as a valuable tool for treating HoFH, offering a ray of hope for individuals facing this complex lipid disorder. Remember, maintaining open communication with your healthcare provider is crucial in navigating any health challenges you may face.

Date :
  1. Date Completed 2017-10-10
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28432645

DOI: Digital Object Identifier

10.1007/s12325-017-0531-x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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