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Aliskiren reduces albuminuria after kidney transplantation.

Author: BiedunkiewiczBogdan, ChamieniaAndrzej L, Debska-SlizienAlicja M, HeleniakZbigniew, LizakowskiSlawomir, MałgorzewiczSylwia, PrzybylskaMilena, RenkeMarcin, RutkowskiBoleslaw, RutkowskiPrzemyslaw, TylickiLeszek

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This double-blind, cross-over study evaluated the influence of aliskiren, a direct renin inhibitor, on albuminuria and other markers of kidney injury in patients after renal transplantation. The results of this study are inconclusive, and further research is needed to confirm the renoprotective effects of aliskiren in renal transplant recipients.
Paper Details　
Original Abstract of the Article :
The renoprotective effects of the direct renin inhibitor, aliskiren, in renal transplant recipients have been supposed, but not finally proven. We performed an exploratory double-blind, losartan controlled, cross-over study to evaluate the influence of aliskiren, direct renin inhibitor, on albuminur...See full text at original site
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引用元：
https://doi.org/10.18388/abp.2016_1297

データ提供：米国国立医学図書館（NLM）

Aliskiren's Potential for Renal Transplant Recipients

This research explores the potential benefits of aliskiren, a direct renin inhibitor, in patients who have received kidney transplants. The study focuses on the effects of aliskiren on albuminuria, a marker of kidney damage, and other surrogate markers of kidney injury in renal transplant recipients. Researchers aimed to determine whether aliskiren could protect the kidneys of transplant recipients and improve their overall health.

A Beacon of Hope for Kidney Transplant Patients

The study's findings suggest that aliskiren might offer a promising new approach to protecting the kidneys of transplant recipients, potentially reducing the risk of long-term complications. This discovery is like finding a hidden oasis in the vast desert of kidney disease, offering a source of relief and rejuvenation for those struggling with this condition.

Navigating the Complexities of Kidney Transplantation

This research underscores the importance of carefully considering the long-term implications of kidney transplantation and exploring new therapies that can protect the kidneys of transplant recipients. Just as a camel caravan needs to be prepared for the challenges of the desert journey, so too must healthcare providers be prepared to address the complex needs of transplant recipients.

Dr. Camel's Conclusion

This research offers a glimmer of hope for kidney transplant recipients, suggesting that aliskiren might play a crucial role in protecting the kidneys and improving long-term outcomes. Just as a camel adapts to survive in the harsh desert environment, so too must we continually seek new and innovative therapies to improve the lives of those who have undergone organ transplantation.
Date :
  1. Date Completed 2017-08-11
  2. Date Revised 2019-03-15
Further Info :

Pubmed ID

28455996

DOI: Digital Object Identifier

10.18388/abp.2016_1297

Related Literature

Article Analysis
・Side Effects of aliskiren
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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