Effect of Valerian in Preventing Neuropsychiatric Adverse Effects of Efavirenz in HIV-Positive Patients: A Pilot Randomized, Placebo-Controlled Clinical Trial.

Author: AbbasianLadan, AhmadiMotahareh, GhaeliPadideh, KhaliliHossein

Paper Details 
Original Abstract of the Article :
BACKGROUND: Several neuropsychiatric adverse effects of efavirenz are known. Preventing these adverse effects may improve patients' adherence to antiretroviral therapy (ART). OBJECTIVES: To evaluate the efficacy and safety of valerian in preventing neuropsychiatric adverse effects of efavirenz in H...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1177/1060028017696105

データ提供:米国国立医学図書館(NLM)

Valerian: A Potential Ally Against Efavirenz's Side Effects

The field of HIV treatment is constantly evolving, with new medications and treatment strategies emerging all the time. One common concern is the occurrence of neuropsychiatric adverse effects, which can hinder patient adherence to antiretroviral therapy (ART). This research delves into the potential benefits of valerian, a natural herb known for its calming properties, in mitigating these side effects. The study employed a randomized, placebo-controlled clinical trial to investigate the efficacy and safety of valerian in HIV-positive patients receiving efavirenz. The results revealed a significant improvement in sleep quality and anxiety levels in the valerian group compared to the placebo group. This finding suggests that valerian may be a viable option for preventing neuropsychiatric adverse effects associated with efavirenz, potentially enhancing patient adherence to treatment and overall well-being.

A Natural Solution for Improved Sleep and Anxiety

The study showed that valerian significantly improved sleep and anxiety in HIV-positive patients receiving efavirenz. This suggests that valerian may be a natural and effective approach to managing the neuropsychiatric side effects of this commonly used antiretroviral drug. The study also highlighted the potential benefits of valerian for improving adherence to ART, which is crucial for effective HIV management.

Valerian: A Promising Natural Remedy

Valerian, a natural herb with a history of traditional medicinal use, has shown potential as a natural remedy for improving sleep quality and reducing anxiety. It could be a valuable option for HIV-positive patients experiencing neuropsychiatric side effects from efavirenz, potentially enhancing their quality of life and adherence to treatment.

Dr. Camel's Conclusion

Just like a camel can traverse vast desert landscapes, valerian, a natural herb, may help navigate the challenges of HIV treatment by reducing the neuropsychiatric side effects of efavirenz. The study findings suggest that valerian could be a valuable tool in the treatment of HIV, potentially improving patient adherence to medication and overall well-being. While more research is needed to fully understand its long-term effects, this research provides valuable insights into the potential benefits of valerian in HIV management.

Date :
  1. Date Completed 2017-09-04
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

28478716

DOI: Digital Object Identifier

10.1177/1060028017696105

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.