Initial experience with first-line pazopanib in the treatment of metastatic renal cell carcinoma: A single institution data.

Author: AgarwalaV, JoshiA, MenonS, NoronhaV, PatilV M, PopatP, PrabhashK, RamaswamyA, SableN

Paper Details 
Original Abstract of the Article :
INTRODUCTION: Pazopanib is one of the recently introduced first-line therapeutic options in the treatment of metastatic renal cell carcinoma (mRCC). There is no published literature from India on the use of pazopanib in mRCC. MATERIALS AND METHODS: We report the efficacy and toxicity analysis of fi...See full text at original site
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引用元:
https://doi.org/10.4103/0019-509X.204769

データ提供:米国国立医学図書館(NLM)

Pazopanib: A New Weapon in the Fight Against Renal Cell Carcinoma

The battle against metastatic renal cell carcinoma (mRCC) is an ongoing quest for effective therapies, with researchers constantly searching for new and innovative treatments. This study delves into the effectiveness and safety of pazopanib, a tyrosine kinase inhibitor, as a first-line therapy for mRCC. The study aims to evaluate the clinical response, tolerability, and potential side effects of pazopanib in a real-world setting, shedding light on the effectiveness of this new drug in the fight against this challenging cancer.

Pazopanib: A Promising First-Line Therapy for mRCC

The study reveals that pazopanib, a tyrosine kinase inhibitor, exhibited promising activity in patients with mRCC, demonstrating a tolerable side effect profile and a significant proportion of patients achieving partial response or stable disease. These findings suggest that pazopanib could be a valuable first-line treatment option for mRCC, offering hope for improved outcomes and potentially extending the lives of patients battling this aggressive cancer. It's like finding a new path in the desert, leading to a more effective and less toxic treatment approach.

Managing Side Effects: A Careful Approach

This research highlights the importance of careful monitoring and management of potential side effects associated with pazopanib therapy. It's like navigating a desert journey, ensuring that we have the necessary supplies and knowledge to address any potential challenges. The study underscores the need for ongoing research to further optimize the use of pazopanib and mitigate any adverse effects.

Dr.Camel's Conclusion

This research explores the efficacy and safety of pazopanib as a first-line therapy for mRCC. The study demonstrates the potential of pazopanib to achieve significant clinical responses while maintaining a tolerable side effect profile. It's a testament to the ongoing progress in cancer research and the commitment to developing new and effective therapies for this challenging disease.

Date :
  1. Date Completed 2018-02-23
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

28485355

DOI: Digital Object Identifier

10.4103/0019-509X.204769

Related Literature

SNS
PICO Info
in preparation
Languages

English

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