Paper Details

  1. Home
  2. Paper Details

[Indeterminate cell histiocytosis - disappearance of skin infiltration following electron beam therapy and an application of 2-chlorodeoxyadenosine: case report].

Author: AdamZdeněk, JežováMarta, KoukalováRenata, KrejčíMarta, KrálZdeněk, KřenLeoš, MayerJiří, PourLuděk, VaškůVladimír, ŘehákZdeněk, ŠlampaPavel

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Indeterminate cell histiocytosis is a rare disease that affects the skin. It was diagnosed in an 80-year-old patient who had skin lesions that spread rapidly. The treatment involved PUVA phototherapy, low-energy electron beam irradiation, and 2-chlorodeoxyadenosine. While the disease went into remission after treatment, it recurred after 6 months.
Paper Details　
Original Abstract of the Article :
Indeterminate cell histiocytosis is a rare disease belonging to the group of malignant histiocytic diseases. The disease predominantly affects the skin. The disease appeared in the described patient at the age of 80 years. Morphs began to develop on the skin and rapidly spread over the whole body in...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/28520453

データ提供：米国国立医学図書館（NLM）

Indeterminate Cell Histiocytosis: A Journey Through the Desert of Rare Diseases

Indeterminate cell histiocytosis (ICH), a rare and complex disease, often leaves healthcare professionals navigating a vast desert of uncertainty. This case report documents the treatment journey of an 80-year-old patient diagnosed with ICH, highlighting the challenges and triumphs of managing this unusual condition.

A Multifaceted Approach to a Rare Disease

This case report showcases the multidisciplinary approach to managing ICH, utilizing a combination of treatments, including PUVA phototherapy, electron beam therapy, and 2-chlorodeoxyadenosine. The patient experienced partial remission following electron beam therapy, but the disease ultimately recurred. The use of 2-chlorodeoxyadenosine led to complete disappearance of skin lesions, demonstrating its potential efficacy in managing ICH. This case exemplifies the importance of persistence and adaptability in treating rare and complex diseases.

Hope in the Desert of Rare Diseases

This case report offers a ray of hope in the desert of rare diseases. While ICH remains challenging to manage, the successful use of 2-chlorodeoxyadenosine in achieving complete remission demonstrates the potential for effective treatments. This study serves as a testament to the dedication of healthcare professionals in seeking solutions for even the rarest and most challenging ailments. The case highlights the importance of collaboration, innovation, and perseverance in navigating the desert of rare diseases.

Dr.Camel's Conclusion

This case report offers a glimpse into the complex and often unpredictable nature of indeterminate cell histiocytosis. The patient's journey through various treatment modalities underscores the importance of a multidisciplinary approach and the unwavering dedication of healthcare professionals in managing rare diseases. The successful use of 2-chlorodeoxyadenosine in achieving complete remission offers a beacon of hope in this challenging landscape, reminding us that even in the vast and sometimes daunting desert of rare diseases, there is potential for positive outcomes.

Date :
  1. Date Completed 2017-09-12
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28520453

DOI: Digital Object Identifier

60937

Related Literature

Article Analysis
・Effects of cladribine injection
SNS
PICO Info
in preparation
Languages

Czech

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.