Tapentadol prolonged-release for moderate-to-severe chronic osteoarthritis knee pain: a double-blind, randomized, placebo- and oxycodone controlled release-controlled study.

Author: LangeBernd, SerrieAlain, SteupAchim

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To assess efficacy and safety of tapentadol prolonged release (PR) for moderate-to-severe chronic osteoarthritis knee pain. METHODS: Patients (n = 990) were randomized (1:1:1) to tapentadol PR, oxycodone controlled release (CR; reference compound for assay sensitivity), or placebo for a ...See full text at original site
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引用元:
https://doi.org/10.1080/03007995.2017.1335189

データ提供:米国国立医学図書館(NLM)

Tapentadol: A New Oasis for Osteoarthritis Pain

This research explores the efficacy and safety of tapentadol prolonged release (PR) for managing moderate-to-severe chronic osteoarthritis knee pain. The researchers conducted a double-blind, randomized, placebo- and oxycodone controlled release-controlled study to compare the effectiveness of tapentadol PR with placebo and oxycodone CR. The study provides valuable insights into the potential benefits and risks of tapentadol PR as a pain management option for osteoarthritis.

Seeking Relief in the Desert of Osteoarthritis Pain

Imagine a camel carrying a heavy load, its knees aching with every step across the unforgiving desert. This study aims to provide relief for those suffering from osteoarthritis knee pain, exploring the potential of tapentadol PR as a pain management solution. The researchers found that tapentadol PR was generally well-tolerated and was associated with a lower incidence of gastrointestinal side effects compared to oxycodone CR, offering a potential pathway to pain relief with fewer adverse effects.

Navigating the Desert of Pain Management

Just as a camel needs to choose the right path through the desert, patients with osteoarthritis knee pain require careful consideration of pain management options. This research highlights the importance of personalized treatment decisions, considering the potential benefits and risks of different medications. The findings underscore the need for ongoing communication with healthcare providers to ensure the most appropriate pain management strategy for each individual.

Dr.Camel's Conclusion

This study sheds light on the potential benefits and risks of tapentadol PR for managing osteoarthritis knee pain. Like a camel seeking a comfortable journey through the desert, patients with osteoarthritis may find relief with the right pain management strategy. The study underscores the importance of individualized care and informed decision-making in choosing the best path to pain relief.

Date :
  1. Date Completed 2018-02-13
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28537501

DOI: Digital Object Identifier

10.1080/03007995.2017.1335189

Related Literature

SNS
PICO Info
in preparation
Languages

English

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