Paper Details 
Original Abstract of the Article :
International guidelines suggest lowering elevated phosphorus level to the normal range in patients on dialysis. Among the phosphate-lowering strategies, phosphate binder is frequently used in addition to dietary phosphate restriction and an adequate dialysis strategy. However, serum phosphate conce...See full text at original site
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引用元:
https://doi.org/10.1016/j.nephro.2017.01.004

データ提供:米国国立医学図書館(NLM)

A New Iron-Based Phosphate Binder for Dialysis Patients

The field of dialysis is constantly evolving, with new medications and treatment approaches emerging. This research delves into the effectiveness of a novel iron-based phosphate binder, sucroferric oxyhydroxide, for treating hyperphosphatemia in dialysis patients. The study employed a rigorous approach, comparing the efficacy of this new agent to sevelamer carbonate, a well-established phosphate binder. The researchers found that sucroferric oxyhydroxide demonstrated comparable efficacy in controlling serum phosphate levels over a one-year period. Interestingly, sucroferric oxyhydroxide required a significantly lower pill burden due to its superior phosphate binding capacity. While the study identified discolored feces and diarrhea as common side effects, these subsided over time, suggesting excellent long-term tolerability.

A Promising Solution for Dialysis Patients

The findings suggest that sucroferric oxyhydroxide could be a valuable alternative for dialysis patients struggling with hyperphosphatemia. The reduced pill burden is particularly beneficial for patient compliance, enhancing the overall treatment experience. However, further research is warranted to evaluate the long-term safety and efficacy of sucroferric oxyhydroxide in a wider patient population.

Navigating the Sands of Phosphate Control

Imagine a desert traveler carrying heavy sacks of phosphate, a burden that can lead to a host of health complications. Sucroferric oxyhydroxide acts like a magic camel, capable of carrying a larger load of phosphate with fewer trips. This reduces the burden on the traveler (patient), making it easier to reach their destination (healthier phosphate levels). While there may be some initial discomfort (diarrhea and discolored feces), these side effects tend to fade with time, leaving the traveler feeling refreshed and invigorated.

Dr.Camel's Conclusion

Sucroferric oxyhydroxide offers a promising solution for managing hyperphosphatemia in dialysis patients. This iron-based phosphate binder demonstrates efficacy comparable to sevelamer carbonate, while requiring a lower pill burden and exhibiting excellent long-term tolerability. While further research is needed, sucroferric oxyhydroxide provides a valuable tool for improving the lives of dialysis patients.

Date :
  1. Date Completed 2018-05-07
  2. Date Revised 2018-05-07
Further Info :

Pubmed ID

28577730

DOI: Digital Object Identifier

10.1016/j.nephro.2017.01.004

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SNS
PICO Info
in preparation
Languages

French

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