Treatment With Bupropion and Varenicline for Smoking Cessation and the Risk of Acute Cardiovascular Events and Injuries: a Swedish Case-Crossover Study.

Author: GalantiMaria Rosaria, HanssonJenny, JanszkyImre, Monárrez-EspinoJoel, MöllerJette, Söderberg-LöfdalKarin

Paper Details 
Original Abstract of the Article :
INTRODUCTION: Bupropion and varenicline are non-nicotine medications used for smoking cessation that mitigate craving and withdrawal symptoms. We aim to investigate whether these drugs increase the risk of selected acute adverse outcomes when used in medical practice. METHODS: Population-based case...See full text at original site
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引用元:
https://doi.org/10.1093/ntr/ntx131

データ提供:米国国立医学図書館(NLM)

Bupropion and Varenicline: A Closer Look at Cardiovascular Safety

In the field of [pharmacology and public health], there is a constant focus on ensuring the safety and efficacy of medications. This study examines the use of [bupropion and varenicline], two non-nicotine medications used for smoking cessation, and their potential association with acute adverse outcomes. Utilizing a [case-crossover study design], the researchers analyzed data from Swedish health registers to investigate the risk of myocardial infarction, stroke, suicide, suicide attempt, fall injury, and road traffic crashes in individuals using these medications. The results suggest that [neither bupropion nor varenicline was associated with consistent higher risks for any of the adverse outcomes]. This study, therefore, provides reassuring evidence regarding the safety profile of these commonly prescribed medications.

Safety First: Bupropion and Varenicline Demonstrate No Elevated Risks

The study provides reassuring results, indicating that [bupropion and varenicline] do not significantly increase the risk of [myocardial infarction, stroke, suicide, suicide attempt, fall injury, or road traffic crashes]. This finding contributes to the understanding of the safety profile of these medications and encourages their continued use in appropriate settings.

Making Informed Choices: Weighing the Risks and Benefits

This research underscores the importance of [careful consideration of both potential risks and benefits] when making decisions about medication use. While the study suggests that [bupropion and varenicline] are relatively safe, it's crucial to discuss any concerns with a healthcare professional to ensure appropriate use and minimize potential risks.

Dr.Camel's Conclusion

Much like a camel navigating a desert, the journey to quit smoking can be challenging and fraught with potential pitfalls. This research, like a well-worn caravan route, provides valuable insights into the safety of two commonly used medications. It offers reassurance that these medications can be considered relatively safe when used responsibly, providing hope for those seeking a healthier future.

Date :
  1. Date Completed 2019-09-26
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

28595356

DOI: Digital Object Identifier

10.1093/ntr/ntx131

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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