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The impact of drugs on male fertility: a review.

Author: BoissierR, LejeuneH, Metzler-GuillemainC, PaciM, PerrinJ, Saïas-MagnanJ, SemetM

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review summarizes existing data on the negative impact of pharmacological treatments (excluding cytotoxic drugs) on male fertility. The review highlights the various mechanisms by which drugs can affect male fertility, including hormonal and non-hormonal effects. It emphasizes the importance of considering drug-induced fertility impacts and the role of sperm cryopreservation in certain cases.
Paper Details　
Original Abstract of the Article :
Beside cytotoxic drugs, other drugs can impact men's fertility through various mechanisms. Via the modification of the hypothalamic-pituitary-gonadal axis hormones or by non-hormonal mechanisms, drugs may directly and indirectly induce sexual dysfunction and spermatogenesis impairment and alteration...See full text at original site
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引用元：
https://doi.org/10.1111/andr.12366

データ提供：米国国立医学図書館（NLM）

The Impact of Drugs on Male Fertility: A Comprehensive Review

This research ventures into the sensitive realm of male fertility, exploring the potential impact of various drugs on reproductive health. The study, akin to a camel caravan traversing a vast desert, provides a comprehensive review of existing literature on the effects of pharmacological treatments on male fertility. The authors emphasize that while cytotoxic drugs are well-known for their detrimental effects on fertility, other medications can also have significant consequences.

Understanding the Potential Risks of Medications for Male Fertility

The study highlights the various mechanisms through which drugs can negatively impact male fertility, ranging from hormonal alterations to non-hormonal effects. The authors categorize the drugs based on their potential to induce sexual dysfunction, spermatogenesis impairment, and epididymal maturation alteration.

Informed Decision-Making for Reproductive Health

This research underscores the importance of considering the potential impact of medications on male fertility, especially for individuals planning to father children. By understanding the potential risks associated with various drugs, healthcare professionals can provide informed counseling and make appropriate recommendations, enabling patients to make informed decisions about their reproductive health.

Dr. Camel's Conclusion

This study serves as a valuable guide for navigating the complex interplay between medications and male fertility. By understanding the potential risks, individuals can make informed choices about their reproductive health, ensuring a smoother journey towards fatherhood.
Date :
  1. Date Completed 2018-01-29
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28622464

DOI: Digital Object Identifier

10.1111/andr.12366

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Languages

English

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