Biocomparison Study of Adult and Paediatric Dose Strengths of the Prostacyclin Receptor Agonist Selexipag.

Author: BoehlerMargaux, BrudererShirin, DingemanseJasper, UlčIvan

Paper Details 
Original Abstract of the Article :
Selexipag is an oral, non-prostanoid, selective prostacyclin receptor agonist recently marketed for the treatment of pulmonary arterial hypertension (PAH) in adults. Selexipag may also be an effective treatment in children with PAH. The aim of this study was to compare the pharmacokinetics of selexi...See full text at original site
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引用元:
https://doi.org/10.1007/s13318-017-0424-z

データ提供:米国国立医学図書館(NLM)

Selexipag: A New Oasis in the Desert of Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH), like a desert mirage, can be a debilitating and life-threatening condition. This research, like a group of scientists exploring a new terrain, compares the pharmacokinetics of selexipag, a novel oral prostacyclin receptor agonist, in adults and children.

Selexipag: A Potential Solution for PAH in Both Adults and Children

The researchers found that selexipag and its active metabolite ACT-333679 exhibited similar pharmacokinetic profiles in adults and children, suggesting that selexipag may be a promising treatment option for children with PAH. This research, like a refreshing oasis in the desert, offers hope for the future of PAH treatment, particularly for children who may have limited treatment options.

Pulmonary Arterial Hypertension: Navigating the Desert of Treatment Options

PAH, like a challenging desert expedition, often requires innovative solutions. This research, like a map guiding us through the desert, provides valuable insights into the potential use of selexipag for treating PAH in both adults and children. This study is a step towards finding new oases of hope in the difficult world of PAH treatment.

Dr. Camel's Conclusion

The study, like a camel caravan discovering a new watering hole, offers a potential solution for treating PAH in both adults and children. Selexipag, like a fresh spring in the desert, holds the promise of improved outcomes and a better quality of life for patients with PAH.

Date :
  1. Date Completed 2018-08-13
  2. Date Revised 2019-01-09
Further Info :

Pubmed ID

28639216

DOI: Digital Object Identifier

10.1007/s13318-017-0424-z

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