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Anticoagulant activity of oral rivaroxaban in healthy dogs.

Author: BlaisM C, ConversyB, Del CastilloJ R E, DunnM, Gara-BoivinC

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study evaluated the anticoagulant effects of rivaroxaban, a direct factor Xa inhibitor, in healthy dogs. Rivaroxaban was found to have a concentration-dependent anticoagulant effect that lasted for 24 hours when administered twice daily. The study suggests that rivaroxaban could be a potential therapeutic option for dogs with thrombotic disorders.
Paper Details　
Original Abstract of the Article :
Rivaroxaban is an oral, direct factor Xa inhibitor used in human thrombotic disorders. In view of the in vitro concentration dependent anticoagulant effects of rivaroxaban in dogs, the time course of its anticoagulant effects was characterized in healthy dogs. Twenty-four healthy Beagles were random...See full text at original site
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引用元：
https://doi.org/10.1016/j.tvjl.2017.03.006

データ提供：米国国立医学図書館（NLM）

Rivaroxaban: A Promising Anticoagulant for Dogs

The world of veterinary medicine is a vast and diverse desert, with many challenges and opportunities for innovation. This study, published in the Journal of Veterinary Pharmacology and Therapeutics, investigates the anticoagulant activity of rivaroxaban, a direct factor Xa inhibitor, in healthy dogs. The researchers conducted a controlled study to evaluate the time course of rivaroxaban's anticoagulant effects in dogs. This research is a significant step towards understanding the potential use of rivaroxaban as an anticoagulant for dogs, a potentially life-saving treatment for our furry companions.

Rivaroxaban: A Potential Anticoagulant for Dogs

The study reveals that rivaroxaban exhibits a concentration-dependent anticoagulant effect in dogs. The researchers found that a single oral dose of rivaroxaban resulted in a significant anticoagulant effect that lasted for up to 18.7 hours, while twice-daily dosing maintained anticoagulation for 24 hours. This is like finding a reliable water source in the desert, offering a solution for managing thrombotic disorders in dogs.

Improving Canine Health: A New Avenue for Treatment

This research offers a promising new avenue for treating thrombotic disorders in dogs. The findings suggest that rivaroxaban could be a safe and effective anticoagulant for dogs, potentially improving their health and quality of life. It's like discovering a new oasis in the desert of veterinary medicine, offering hope and healing for our canine companions.

Dr. Camel's Conclusion

This study is a testament to the importance of research and development in veterinary medicine. The discovery of rivaroxaban's potential as an anticoagulant for dogs is a significant step forward, offering new possibilities for treating thrombotic disorders in our canine companions. We must continue to explore new avenues and push the boundaries of knowledge to improve the health and well-being of all animals.

Date :
  1. Date Completed 2017-10-16
  2. Date Revised 2017-10-16
Further Info :

Pubmed ID

28671072

DOI: Digital Object Identifier

10.1016/j.tvjl.2017.03.006

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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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