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Gelatin modified lipid nanoparticles for anti- viral drug delivery.
Author: K SJoshy, KalarikkalNandakumar, PothenLaly A, SSnigdha, ThomasSabu
Original Abstract of the Article :
The major challenges to clinical application of zidovudine are its moderate aqueous solubility and relative short half-life and serious side effects due to frequent administrations. We investigated the preparation of zidovudine-loaded nanoparticles based on lipids which were further modified with th...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.chemphyslip.2017.07.002
データ提供:米国国立医学図書館(NLM)
Gelatin-Modified Lipid Nanoparticles for Anti-Viral Drug Delivery
The fight against HIV/AIDS is like a desert battle, where scientists are constantly seeking new weapons and strategies to defeat the virus. Zidovudine, a vital antiviral medication, is like a skilled warrior, but it faces challenges in reaching its target and minimizing side effects. This research, like a brilliant inventor, explores a novel approach to deliver zidovudine more effectively: gelatin-modified lipid nanoparticles. These nanoparticles, like cleverly designed caravans, carry the medication, protecting it from degradation and ensuring it reaches its destination.
Nanotechnology: A New Weapon in the Fight Against HIV
The study, like a meticulous engineer, carefully designs and analyzes the nanoparticles, ensuring their stability and efficacy. These nanoparticles, like cleverly designed camels, efficiently carry zidovudine to the target cells, demonstrating sustained release and enhanced cellular uptake. The research, like a promising oasis in a parched land, suggests that these nanoparticles could be a potential breakthrough in the fight against HIV/AIDS.
Improving Anti-Viral Therapy
This research, like a desert caravan bringing vital supplies, offers a promising new approach to HIV/AIDS treatment. These nanoparticles, like efficient messengers, could potentially improve drug delivery, reduce side effects, and enhance treatment outcomes.
Dr.Camel's Conclusion
This research, like a desert oasis offering hope, shows the promise of nanotechnology in the fight against HIV/AIDS. These gelatin-modified lipid nanoparticles, like a well-equipped caravan, could potentially revolutionize anti-viral therapy, bringing us closer to a world free from this devastating disease.
Date :
- Date Completed 2017-09-25
- Date Revised 2018-09-03
Further Info :
Related Literature
English
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