Real-world utilization of darbepoetin alfa in cancer chemotherapy patients.

Author: ChandlerDavid, LiXiaoyan Shawn, LinJunji, MacLachlanSharon, NordstromBeth L, PanXiaoyun Lucy, SharmaAnjali, XuHairong

Paper Details 
Original Abstract of the Article :
OBJECTIVES: To provide an understanding of darbepoetin alfa dose patterns in cancer patients undergoing myelosuppressive chemotherapy starting from 2011. STUDY DESIGN: This is a retrospective cohort study using a proprietary outpatient oncology database. METHODS: Metastatic, solid tumor cancer pat...See full text at original site
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引用元:
https://doi.org/10.1177/1078155217725571

データ提供:米国国立医学図書館(NLM)

Understanding Darbepoetin Alfa in Cancer Chemotherapy: A Real-World Utilization Study

The field of oncology is constantly seeking ways to improve the quality of life for cancer patients, particularly those undergoing myelosuppressive chemotherapy, a treatment that can suppress bone marrow function. This research explores the real-world utilization of darbepoetin alfa, an erythropoiesis-stimulating agent, in managing chemotherapy-induced anemia. The authors conducted a retrospective cohort study using a proprietary outpatient oncology database, analyzing the dose patterns of darbepoetin alfa in cancer patients receiving myelosuppressive chemotherapy.

Darbepoetin Alfa in Cancer Care: A Real-World Perspective

The study provides valuable insights into the real-world use of darbepoetin alfa in cancer patients. The authors found that the average weekly dose of darbepoetin alfa was lower than the labeled dosage for most adults. The analysis also revealed that the dose patterns did not vary significantly across different chemotherapy regimens, baseline hemoglobin levels, or solid tumor types. This information can be used to inform clinical practice and optimize the use of darbepoetin alfa in cancer patients.

Optimizing Cancer Treatment: Balancing Effectiveness and Safety

This research underscores the importance of understanding the real-world utilization of medications in cancer treatment. By analyzing actual dose patterns, we can identify potential areas for improvement and ensure the most effective and safe use of drugs like darbepoetin alfa. This research encourages ongoing monitoring and evaluation of medication use in cancer care, promoting evidence-based practice and optimizing patient outcomes.

Dr. Camel's Conclusion

This research is like a compass guiding us through the complex world of cancer treatment. By understanding the real-world utilization of darbepoetin alfa, we can navigate the landscape of chemotherapy with greater precision, ensuring that patients receive the optimal care they need. This study reminds us that in the fight against cancer, every detail matters, and by meticulously analyzing data, we can pave the way for better treatment strategies and improved patient outcomes.

Date :
  1. Date Completed 2019-01-18
  2. Date Revised 2019-01-18
Further Info :

Pubmed ID

28814194

DOI: Digital Object Identifier

10.1177/1078155217725571

Related Literature

SNS
PICO Info
in preparation
Languages

English

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