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Benefit-Risk Profile of Sphingosine-1-Phosphate Receptor Modulators in Relapsing and Secondary Progressive Multiple Sclerosis.
Author: BakshiRajesh, ComiGiancarlo, HartungHans-Peter, WiendlHeinz, WilliamsIan M
Original Abstract of the Article :
Since the approval of fingolimod, several selective sphingosine-1-phosphate receptor modulators have entered clinical development for multiple sclerosis. However, side effects can occur with sphingosine-1-phosphate receptor modulators. By considering short-term data across the drug class and longer ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661009/
データ提供:米国国立医学図書館(NLM)
Sphingosine-1-Phosphate Receptor Modulators: A Promising Therapy for Multiple Sclerosis
The field of neurology is constantly searching for new and effective therapies for chronic neurological disorders. This research examines the benefit-risk profile of sphingosine-1-phosphate receptor modulators, a class of drugs that show promise for treating multiple sclerosis (MS). The study reviews available data to assess the efficacy, safety, and long-term implications of these drugs for managing MS.
Sphingosine-1-Phosphate Receptor Modulators: A Balancing Act
The study highlights the effectiveness of sphingosine-1-phosphate receptor modulators in reducing MS relapses and slowing disease progression. However, it also acknowledges potential side effects, including cardiac events, macular edema, infection, and malignancy. The study emphasizes the importance of carefully weighing these risks and benefits when considering treatment with these drugs.
Long-Term Management of MS: A Promising Future
This research suggests that sphingosine-1-phosphate receptor modulators offer a promising long-term treatment option for MS. The study's review of short-term and long-term data indicates that these drugs can be effective and safe for long-term use. Furthermore, the study highlights the potential for improved patient satisfaction and treatment persistence with these drugs compared to injectable therapies.
Dr. Camel's Conclusion
Imagine a desert oasis, where the cool waters of a spring offer respite from the harsh heat. This research explores the potential of sphingosine-1-phosphate receptor modulators as a therapeutic oasis for individuals with MS. While these drugs offer promise for managing MS, it's important to approach treatment with a thoughtful understanding of their potential risks and benefits. Just as a traveler in the desert needs to carefully navigate the landscape, clinicians need to assess the individual needs of each patient to ensure safe and effective treatment with these drugs. This research provides valuable information to guide informed decision-making and optimize patient care.
Date :
- Date Completed 2018-11-19
- Date Revised 2019-07-25
Further Info :
Related Literature
English
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