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Deuterated (d6)-dextromethorphan elicits antidepressant-like effects in mice.
Author: MatsumotoRae R, NguyenLinda, ScandinaroAnna L
Original Abstract of the Article :
The over-the-counter antitussive dextromethorphan (DM) may have rapid antidepressant actions based on its overlapping pharmacology with ketamine, which has shown fast antidepressant effects but whose widespread use remains limited by problematic side effects. We have previously shown that DM produce...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.pbb.2017.09.005
データ提供:米国国立医学図書館(NLM)
Modified Dextromethorphan: A Potential Antidepressant?
The field of [antidepressant drug development] is always looking for new solutions, and this study explores a modified form of the common cough suppressant, [dextromethorphan], as a potential treatment for depression. The researchers used a [modified form of dextromethorphan] in [animal studies] to see if it had [antidepressant-like effects]. They found that this modified form did show these effects, even in the presence of [quinidine], a drug that can slow down its metabolism. This is exciting news, as [dextromethorphan] is already known to be relatively safe. The study suggests that this modified form might be a promising new treatment for depression, but more research is needed to confirm its effectiveness.
Potential New Antidepressant: What Does It Mean?
The study's findings are intriguing, as they suggest that modified [dextromethorphan] may be a new treatment option for depression. If this research proves true, it could mean that a relatively safe and accessible medication could be used to help people with depression. However, it's important to note that this study was conducted in [mice], and further studies are needed in [humans] to confirm these findings. We're still on the journey to find a new and effective treatment for depression, and this research offers a promising direction.
Can This Help Me?
It's exciting to see new research exploring potential treatments for depression. While it's too early to say if modified [dextromethorphan] will be available for human use, it's important to remember that [depression] is a serious condition, and effective treatment is available. If you or someone you know is struggling with [depression], please seek professional help. It's not uncommon to feel [overwhelmed] by life's challenges, and seeking help is a sign of strength, not weakness.
Dr.Camel's Conclusion
This study is like a refreshing oasis in the desert of [antidepressant research]. It's promising, but we need to keep digging for more evidence before we can declare it a treasure! There's still a lot we don't know, so let's continue exploring the vast landscape of mental health!
Date :
- Date Completed 2018-06-04
- Date Revised 2018-06-04
Further Info :
Related Literature
English
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