Paper Details 
Original Abstract of the Article :
The purpose of this study is to develop a new method of preparing salvianolic acid extracts (SAE) water-in-oil-in-water (W/O/W) multiple emulsion (ME). SAE injection is used in the treatment of brain infarct and promotion of blood circulation in China. However, the injection is not convenient, and t...See full text at original site
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引用元:
https://doi.org/10.1248/bpb.b17-00162

データ提供:米国国立医学図書館(NLM)

Salvianolic Acid Extracts: A New Approach to Oral Bioavailability

This study explores the development of a new method for delivering salvianolic acid extracts (SAE), a traditional Chinese medicine used for treating brain infarct and promoting blood circulation. It's like searching for a hidden oasis in the desert, seeking a more effective way to deliver this valuable medicine. The researchers investigated the use of water-in-oil-in-water (W/O/W) multiple emulsions (ME) to improve the oral bioavailability of SAE. Their findings demonstrated that SAE ME significantly enhanced the bioavailability and effectiveness of SAE, offering a potential alternative to traditional injection methods.

Salvianolic Acid Extracts: Enhanced Bioavailability and Effectiveness

The study found that SAE ME significantly increased the oral bioavailability of salvianolic acid extracts (SAE) compared to free drug administration. This improvement in bioavailability could translate to enhanced therapeutic effects, potentially leading to more effective treatment for conditions such as brain infarct and blood circulation disorders. It's like discovering a new route through the desert, leading to a more efficient and effective way to deliver this valuable medicine.

Optimizing Oral Bioavailability: A Step Towards Improved Healthcare

This research highlights the importance of developing innovative drug delivery systems to improve the bioavailability and effectiveness of traditional medicines. By exploring novel approaches like W/O/W multiple emulsions, we can enhance the therapeutic potential of these medicines, potentially leading to improved outcomes for patients. It's like building a new bridge across the desert, connecting traditional medicine with modern innovation to create a path towards better healthcare.

Dr.Camel's Conclusion

This research highlights the potential of W/O/W multiple emulsions to enhance the oral bioavailability and effectiveness of salvianolic acid extracts. This innovative approach offers a promising alternative to traditional injection methods, potentially improving treatment outcomes for patients. It's like discovering a hidden oasis in the desert, providing a source of relief and a potential cure for this persistent infection.

Date :
  1. Date Completed 2018-07-17
  2. Date Revised 2018-07-17
Further Info :

Pubmed ID

28943530

DOI: Digital Object Identifier

10.1248/bpb.b17-00162

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Languages

English

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