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Meta-Analysis of the Efficacy and Safety of Mirabegron Add-On Therapy to Solifenacin for Overactive Bladder.
Author: CuiYuanshan, GaoZhenli, LiuChu, LiuRuihua, XuYankai
Original Abstract of the Article :
PURPOSE: We performed a meta-analysis to evaluate the efficacy and safety of mirabegron add-on therapy to solifenacin for patients with overactive bladder (OAB). METHODS: We conducted a systematic literature review to identify all randomized, double-blind, controlled trials (RCTs) of this combinati...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636960/
データ提供:米国国立医学図書館(NLM)
Mirabegron as Add-On Therapy for Overactive Bladder
The quest for effective treatments for [overactive bladder (OAB)] is an ongoing pursuit in the field of [urology]. This study delves into the potential benefits of adding [mirabegron] to the existing treatment regimen of [solifenacin] for patients with OAB. Researchers conducted a [meta-analysis] of five randomized controlled trials, pooling data from 3,309 patients. They discovered that combination therapy was significantly more effective in reducing OAB symptoms compared to solifenacin alone, and it was well tolerated with minimal side effects. It's like combining the strengths of two different camels to carry a heavier load - the combination of mirabegron and solifenacin provides a more robust and effective solution for OAB.
Combination Therapy: A More Effective Approach for OAB
The meta-analysis suggests that combining mirabegron with solifenacin offers a more effective treatment strategy for OAB. This finding could be beneficial for patients who are not adequately responding to solifenacin alone. It's like discovering a new and more efficient route through the desert, leading to a more comfortable and successful journey.
A Promising Solution for OAB Management
This research provides evidence that combination therapy with mirabegron and solifenacin can be a valuable option for managing OAB symptoms. The improved efficacy and safety profile of this approach could offer better outcomes for patients. As a wise camel, I always say, it's important to seek out the best solutions, even if it requires combining different resources.
Dr.Camel's Conclusion
This meta-analysis suggests that adding mirabegron to solifenacin therapy can significantly improve the management of overactive bladder symptoms with a favorable safety profile.
Date :
- Date Completed n.d.
- Date Revised 2020-09-30
Further Info :
Related Literature
English
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