Protective effect of antioxidant rich aqueous curry leaf (<i>Murraya koenigii</i>) extract against gastro-toxic effects of piroxicam in male Wistar rats.

Author: BandyopadhyayDebasish, BanerjeeBhaswati, BasuAnjali, BoseGargi, ChatterjeeSubhrangshu, ChattyopadhyayAindrila, DuttaMousumi, FirdausSyed Benazir, GhoshDebosree, JanaJagannath, JanaKuladip, LahiriHiya, PattariSanjib, PaulSudeshna

Paper Details 
Original Abstract of the Article :
Piroxicam (chemically 4-hydroxy-2-methyl-<i>N</i>-2-pyridinyl-2<i>H</i>-1,2-benzothiazine-3-carboxamide), a classical non-steroidal anti-inflammatory drug (NSAID) is orally administered to arthritic patients. Inhibition of prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) synthesis and subsequent free h...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598401/

データ提供:米国国立医学図書館(NLM)

Curry Leaf Extract: A Potential Ally Against Piroxicam-Induced Gastric Damage

Piroxicam, a common non-steroidal anti-inflammatory drug (NSAID), is often used to treat arthritis. However, it can have damaging effects on the stomach. This study explored the protective effects of curry leaf extract, which is rich in antioxidants, against piroxicam-induced gastric damage in rats. The researchers found that curry leaf extract significantly reduced the severity of gastric ulcers caused by piroxicam, suggesting its potential to mitigate the adverse effects of this medication. This is like finding a shady grove in the desert, offering protection from the harsh sun and its damaging rays.

A Natural Remedy for Piroxicam-Induced Gastric Damage

This study suggests that curry leaf extract could be a valuable natural remedy for mitigating the gastric damage caused by piroxicam. While further research is needed to confirm these findings in humans, this study offers a glimmer of hope for patients who need to take NSAIDs but are concerned about their potential side effects. It's like discovering a secret oasis in the desert, where a natural remedy can provide relief from the effects of harsh conditions.

A Holistic Approach to Health

This study underscores the importance of a holistic approach to health. It highlights how natural remedies, like curry leaf extract, can play a crucial role in mitigating the side effects of medications. It's like recognizing that even in the harshest of deserts, there are natural resources that can provide sustenance and support.

Dr.Camel's Conclusion

This study offers promising evidence that curry leaf extract could be a valuable natural remedy for mitigating the gastric damage caused by piroxicam. While further research is needed to confirm these findings in humans, this study suggests a potential pathway for reducing the side effects of commonly used medications. It's a journey through the desert of pharmaceutical side effects, and this study offers a potential oasis of hope for patients seeking natural solutions.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

28962312

DOI: Digital Object Identifier

PMC5598401

Related Literature

SNS
PICO Info
in preparation
Languages

English

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